Reactome | MECOM:PTEN gene [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-HSA-8943817] MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter - Homo sapiens
created	[InstanceEdit:8943812] Orlic-Milacic, Marija, 2016-10-30
dbId	8943810
displayName	MECOM:PTEN gene [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-8943897] MECOM [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-5632949] PTEN gene [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-8943810] MECOM:PTEN gene [nucleoplasm] - Mus musculus [Complex:R-RNO-8943810] MECOM:PTEN gene [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-8943810] MECOM:PTEN gene [nucleoplasm] - Canis familiaris [Complex:R-BTA-8943810] MECOM:PTEN gene [nucleoplasm] - Bos taurus [Complex:R-SSC-8943810] MECOM:PTEN gene [nucleoplasm] - Sus scrofa [Complex:R-GGA-8943810] MECOM:PTEN gene [nucleoplasm] - Gallus gallus [Complex:R-DME-8943810] MECOM:PTEN gene [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-8943810] MECOM:PTEN gene [nucleoplasm] - Caenorhabditis elegans
isChimeric	false
literatureReference	[LiteratureReference:8942920] Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins
maxDepth	2
modified	[InstanceEdit:8943899] Orlic-Milacic, Marija, 2016-10-31
name	MECOM:PTEN gene
producedByEvent	[Reaction:R-HSA-8943811] MECOM (EVI1) binds the PTEN gene promoter - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8943810

(output)	[Reaction:R-HSA-8943811] MECOM (EVI1) binds the PTEN gene promoter
(input)	[Reaction:R-HSA-8943817] MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter