Reactome | HLA A-2,A-3,B-60 [endoplasmic reticulum membrane]

Schema > DefinedSet > Entries

compartment	[Compartment:12045] endoplasmic reticulum membrane
componentOf	[Complex:R-HSA-8943114] US11:HLA [endoplasmic reticulum membrane] - Homo sapiens
created	[InstanceEdit:8943110] May, Bruce, 2016-10-24
dbId	8943116
displayName	HLA A-2,A-3,B-60 [endoplasmic reticulum membrane]
hasMember	[EntityWithAccessionedSequence:R-HSA-8943090] HLA-A A-3 [endoplasmic reticulum membrane] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-8943140] HLA-B B-60 [endoplasmic reticulum membrane] - Homo sapiens
inDisease	false
isOrdered	true
literatureReference	[LiteratureReference:8943130] A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation [LiteratureReference:8943094] TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I
maxDepth	2
modified	[InstanceEdit:9827252] D'Eustachio, Peter, 2023-01-30
name	HLA A-2,A-3,B-60
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-8943116
updateTrackers	[UpdateTracker:9904849] Update Tracker - [DefinedSet:8943116] HLA A-2,A-3,B-60 [endoplasmic reticulum membrane] - v84:[removeHasMember]

(updatedInstance)	[UpdateTracker:9904849] Update Tracker - [DefinedSet:8943116] HLA A-2,A-3,B-60 [endoplasmic reticulum membrane] - v84:[removeHasMember]
(hasComponent)	[Complex:R-HSA-8943114] US11:HLA [endoplasmic reticulum membrane]

Cite Us!