Reactome | MMP7 cleaves OPTC

Schema > Reaction > Entries

MMP7 cleaves OPTC Show undefined attributes

authored	[InstanceEdit:8940521] Jupe, Steve, 2016-09-27
catalystActivity	[CatalystActivity:8940518] metalloendopeptidase activity of MMP7(95-267) [extracellular region]
category	transition
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:8940521] Jupe, Steve, 2016-09-27
dbId	8940561
displayName	MMP7 cleaves OPTC
edited	[InstanceEdit:8941325] Jupe, Steve, 2016-09-30
eventOf	[Pathway:R-HSA-1474228] Degradation of the extracellular matrix - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-8940538] OPTC [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8940527] Characterization of opticin digestion by proteases involved in osteoarthritis development
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	MMP7 cleaves OPTC
orthologousEvent	[Reaction:R-GGA-8940561] MMP7 cleaves OPTC - Gallus gallus [Reaction:R-XTR-8940561] MMP7 cleaves OPTC - Xenopus tropicalis [Reaction:R-SSC-8940561] MMP7 cleaves OPTC - Sus scrofa [Reaction:R-BTA-8940561] MMP7 cleaves OPTC - Bos taurus [Reaction:R-CFA-8940561] MMP7 cleaves OPTC - Canis familiaris [Reaction:R-RNO-8940561] MMP7 cleaves OPTC - Rattus norvegicus [Reaction:R-MMU-8940561] MMP7 cleaves OPTC - Mus musculus
output	[EntityWithAccessionedSequence:R-HSA-8942317] OPTC(115-332) [extracellular region] [EntityWithAccessionedSequence:R-HSA-8940514] OPTC(20-32) [extracellular region] [EntityWithAccessionedSequence:R-HSA-8942306] OPTC(33-87) [extracellular region] [EntityWithAccessionedSequence:R-HSA-8940534] OPTC(88-114) [extracellular region]
releaseDate	2016-12-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8942310] Ricard-Blum, Sylvie, 2016-10-12
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8940561
summation	[Summation:8940563] Opticin (OPTC) is a a member of the small leucine-rich repea...

Referrals

(hasEvent)

[Pathway:R-HSA-1474228] Degradation of the extracellular matrix