Reactome | RUNX1:CBFB:CR1 gene [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8939089] Orlic-Milacic, Marija, 2016-09-15
dbId	8939080
displayName	RUNX1:CBFB:CR1 gene [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-8939094] CR1 gene [nucleoplasm] [Complex:R-HSA-8865330] RUNX1:CBFB [nucleoplasm]
inDisease	false
isChimeric	false
literatureReference	[LiteratureReference:8939079] AML1, the target of chromosomal rearrangements in human leukemia, regulates the expression of human complement receptor type 1 (CR1) gene [LiteratureReference:8939085] Correlation between cellular localization of TEL/AML1 fusion protein and repression of AML1-mediated transactivation of CR1 gene
maxDepth	3
modified	[InstanceEdit:8955517] Orlic-Milacic, Marija, 2017-01-11
name	RUNX1:CBFB:CR1 gene
positivelyRegulates	[PositiveGeneExpressionRegulation:R-HSA-8939102] Positive gene expression regulation by 'RUNX1:CBFB:CR1 gene [nucleoplasm]'
producedByEvent	[Reaction:R-HSA-8939082] RUNX1 binds the CR1 gene promoter - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8939080

(regulator)	[PositiveGeneExpressionRegulation:R-HSA-8939102] Positive gene expression regulation by 'RUNX1:CBFB:CR1 gene [nucleoplasm]'
(output)	[Reaction:R-HSA-8939082] RUNX1 binds the CR1 gene promoter

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