Reactome | RUNX2:CBFB binds the LGALS3 gene promoter

Schema > Reaction > Entries

authored	[InstanceEdit:8938373] Orlic-Milacic, Marija, 2016-09-09
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8938373] Orlic-Milacic, Marija, 2016-09-09
dbId	8938371
displayName	RUNX2:CBFB binds the LGALS3 gene promoter
edited	[InstanceEdit:9015316] Orlic-Milacic, Marija, 2017-08-09
eventOf	[Pathway:R-HSA-8941333] RUNX2 regulates genes involved in differentiation of myeloid cells - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-8938382] LGALS3 gene expression is stimulated by RUNX1 and RUNX2 - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-8938366] LGALS3 gene [nucleoplasm] [Complex:R-HSA-8865420] RUNX2:CBFB [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8938376] RUNX1 and RUNX2 upregulate Galectin-3 expression in human pituitary tumors [LiteratureReference:8938402] Runx2 is expressed in human glioma cells and mediates the expression of galectin-3
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	RUNX2:CBFB binds the LGALS3 gene promoter
output	[Complex:R-HSA-8938367] RUNX2:CBFB:LGALS3 gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-8865425] RUNX2 binds CBFB - Homo sapiens
releaseDate	2017-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9015314] Ducy, Patricia, 2017-08-04
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8938371
summation	[Summation:8938384] The RUNX2:CBFB complex binds the RUNX2 response element in t...

(hasEvent)	[Pathway:R-HSA-8941333] RUNX2 regulates genes involved in differentiation of myeloid cells
(precedingEvent)	[BlackBoxEvent:R-HSA-8938382] LGALS3 gene expression is stimulated by RUNX1 and RUNX2

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