Reactome | H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm]

Schema > Complex > Entries

H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] Show undefined attributes

catalystActivities	[CatalystActivity:8937051] histone H3K4 methyltransferase activity of H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-HSA-8937050] Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter - Homo sapiens
created	[InstanceEdit:8937035] Orlic-Milacic, Marija, 2016-08-26
dbId	8937036
displayName	H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-HSA-8937042] MIR27A gene [nucleoplasm] [Complex:R-HSA-1214200] Nucleosome with H3K4me2 [nucleoplasm] [Complex:R-HSA-8936477] RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-8937036] H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] - Mus musculus [Complex:R-RNO-8937036] H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-8937036] H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] - Canis familiaris [Complex:R-BTA-8937036] H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] - Bos taurus [Complex:R-SSC-8937036] H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] - Sus scrofa [Complex:R-DRE-8937036] H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] - Danio rerio [Complex:R-XTR-8937036] H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-8937036] H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] - Gallus gallus [Complex:R-DME-8937036] H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-8937036] H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] - Caenorhabditis elegans
isChimeric	false
literatureReference	[LiteratureReference:8936397] Histone arginine methylation keeps RUNX1 target genes in an intermediate state
maxDepth	6
modified	[InstanceEdit:8955517] Orlic-Milacic, Marija, 2017-01-11
name	H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B
producedByEvent	[Reaction:R-HSA-8937037] RUNX1 and GATA1 bind the promoter of the MIR27A gene - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8937036
updateTrackers	[UpdateTracker:9904711] Update Tracker - [Complex:8937036] H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] - v84:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9904711] Update Tracker - [Complex:8937036] H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] - v84:[updateContainedComponent]
(input)	[Reaction:R-HSA-8937050] Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter
(physicalEntity)	[CatalystActivity:8937051] histone H3K4 methyltransferase activity of H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm]
(output)	[Reaction:R-HSA-8937037] RUNX1 and GATA1 bind the promoter of the MIR27A gene

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