Reactome | RUNX1 binds the TJP1 (ZO-1) gene promoter

Schema > Reaction > Entries

authored	[InstanceEdit:8938982] Orlic-Milacic, Marija, 2016-09-14
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8935961] Orlic-Milacic, Marija, 2016-08-15
dbId	8935960
displayName	RUNX1 binds the TJP1 (ZO-1) gene promoter
edited	[InstanceEdit:9005626] Orlic-Milacic, Marija, 2017-05-09
eventOf	[Pathway:R-HSA-8935964] RUNX1 regulates expression of components of tight junctions - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-8935972] TJP1 (ZO-1) gene expression is stimulated by RUNX1 - Homo sapiens
input	[Complex:R-HSA-8865330] RUNX1:CBFB [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-8935963] TJP1 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8935935] MiR-18a increased the permeability of BTB via RUNX1 mediated down-regulation of ZO-1, occludin and claudin-5
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	RUNX1 binds the TJP1 (ZO-1) gene promoter
output	[Complex:R-HSA-8935959] RUNX1:CBFB:TJP1 gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-8865320] CBFB binds RUNX1 - Homo sapiens
releaseDate	2017-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9005627] Ito, Yoshiaki, 2016-12-20 [InstanceEdit:9005628] Chuang, Linda Shyue Huey, 2016-12-20
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8935960
summation	[Summation:8935973] The RUNX1:CBFB complex binds the promoter of the TJP1 gene, ...

(precedingEvent)	[BlackBoxEvent:R-HSA-8935972] TJP1 (ZO-1) gene expression is stimulated by RUNX1
(hasEvent)	[Pathway:R-HSA-8935964] RUNX1 regulates expression of components of tight junctions

Cite Us!