Reactome | miR-18a binds RUNX1 mRNA

Schema > Reaction > Entries

authored	[InstanceEdit:8938982] Orlic-Milacic, Marija, 2016-09-14
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:8935937] Orlic-Milacic, Marija, 2016-08-15
dbId	8935930
displayName	miR-18a binds RUNX1 mRNA
edited	[InstanceEdit:9005626] Orlic-Milacic, Marija, 2017-05-09
eventOf	[Pathway:R-HSA-8934593] Regulation of RUNX1 Expression and Activity - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-8935785] RUNX1 mRNA translation is inhibited by miR-17, miR-18a, miR-20a, miR-27a, miR-106a, miR-215, miR-302b, miR-378 and miR-675 - Homo sapiens
input	[CandidateSet:R-HSA-8935934] miR-18a RISC [cytosol] [EntityWithAccessionedSequence:R-HSA-8935779] RUNX1 mRNA [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8935935] MiR-18a increased the permeability of BTB via RUNX1 mediated down-regulation of ZO-1, occludin and claudin-5
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	miR-18a binds RUNX1 mRNA
output	[Complex:R-HSA-8935945] RUNX1 mRNA:miR-18a RISC [cytosol]
releaseDate	2017-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9005627] Ito, Yoshiaki, 2016-12-20 [InstanceEdit:9005628] Chuang, Linda Shyue Huey, 2016-12-20
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8935930
summation	[Summation:8935949] Mature single stranded microRNA miR-18a-5p, one of the two p...

(hasEvent)	[Pathway:R-HSA-8934593] Regulation of RUNX1 Expression and Activity
(precedingEvent)	[BlackBoxEvent:R-HSA-8935785] RUNX1 mRNA translation is inhibited by miR-17, miR-18a, miR-20a, miR-27a, miR-106a, miR-215, miR-302b, miR-378 and miR-675

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