Reactome | MYC:MAX binds the CDC25A gene

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MYC:MAX binds the CDC25A gene Show undefined attributes

authored	[InstanceEdit:187972] Matthews, L, 2006-09-29 13:59:34
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8932401] Orlic-Milacic, Marija, 2016-07-22
dbId	8932400
displayName	MYC:MAX binds the CDC25A gene
edited	[InstanceEdit:188346] Matthews, L, 2006-10-10 08:05:07
eventOf	[Pathway:R-HSA-69202] Cyclin E associated events during G1/S transition - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-188345] The CDC25A gene transcription is stimulated by MYC and E2F1 and inhibited by the DREAM complex - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-4088168] CDC25A gene [nucleoplasm] [Complex:R-HSA-188378] MYC:MAX [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:188344] Cdc25 cell-cycle phosphatase as a target of c-myc
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	MYC:MAX binds the CDC25A gene
output	[Complex:R-HSA-8932399] MYC:MAX:CDC25A gene [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-HSA-1980067] NOTCH1 stimulates MYC transcription - Homo sapiens [BlackBoxEvent:R-HSA-4411357] TCF7L1/TCF7L2/LEF1:CTNNB1 promote transcription of the MYC gene - Homo sapiens [BlackBoxEvent:R-HSA-1484099] MYC trancscription is negatively regulated by SMAD2/3:SMAD4:RBL1:E2F4/5:DP1/2 complex - Homo sapiens
releaseDate	2016-09-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:188313] Coqueret, O, 2006-10-06 08:59:06
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8932400
summation	[Summation:8932398] The MYC:MAX heterodimer binds to MYC response elements in th...

Referrals

(hasEvent)	[Pathway:R-HSA-69202] Cyclin E associated events during G1/S transition
(precedingEvent)	[BlackBoxEvent:R-HSA-188345] The CDC25A gene transcription is stimulated by MYC and E2F1 and inhibited by the DREAM complex

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