Reactome | ECE2 cleaves EDN1(53-90)

Schema > Reaction > Entries

ECE2 cleaves EDN1(53-90) Show undefined attributes

authored	[InstanceEdit:8874428] Jupe, Steve, 2016-05-23
catalystActivity	[CatalystActivity:8877621] metalloendopeptidase activity of ECE2 [transport vesicle membrane]
category	transition
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:8877619] Jupe, Steve, 2016-06-27
dbId	8877620
displayName	ECE2 cleaves EDN1(53-90)
edited	[InstanceEdit:8942962] Jupe, Steve, 2016-10-21
eventOf	[Pathway:R-HSA-375276] Peptide ligand-binding receptors - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-8878413] EDN1(53-90) [transport vesicle]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8877824] Endothelin-converting enzyme-2 is a membrane-bound, phosphoramidon-sensitive metalloprotease with acidic pH optimum
maxDepth	1
modified	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
name	ECE2 cleaves EDN1(53-90)
orthologousEvent	[Reaction:R-XTR-8877620] ECE2 cleaves EDN1(53-90) - Xenopus tropicalis [Reaction:R-SSC-8877620] ECE2 cleaves EDN1(53-90) - Sus scrofa [Reaction:R-BTA-8877620] ECE2 cleaves EDN1(53-90) - Bos taurus [Reaction:R-CFA-8877620] ECE2 cleaves EDN1(53-90) - Canis familiaris [Reaction:R-RNO-8877620] ECE2 cleaves EDN1(53-90) - Rattus norvegicus [Reaction:R-MMU-8877620] ECE2 cleaves EDN1(53-90) - Mus musculus
output	[EntityWithAccessionedSequence:R-HSA-8878414] EDN1 [transport vesicle]
releaseDate	2016-12-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8948667] D'Eustachio, Peter, 2016-11-15
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8877620
summation	[Summation:8877826] Endothelin-converting enzyme 2 (ECE2) belongs to the type II...

Referrals

(hasEvent)

[Pathway:R-HSA-375276] Peptide ligand-binding receptors

Cite Us!