Reactome | PLEKHA3,8 bind PI4P, ARF1

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PLEKHA3,8 bind PI4P, ARF1 Show undefined attributes

authored	[InstanceEdit:8870505] Jassal, Bijay, 2016-05-10
catalystActivity	[CatalystActivity:9960139] molecular carrier activity of PLEKHA3,8 [Golgi membrane]
catalystActivityReference	[CatalystActivityReference:9960140] molecular carrier activity of PLEKHA3,8 [Golgi membrane] ARF mediates recruitment of PtdIns-4-OH kinase-beta and stimulates synthesis of PtdIns(4,5)P2 on the Golgi complex
category	transition
compartment	[Compartment:20699] Golgi membrane
created	[InstanceEdit:8870505] Jassal, Bijay, 2016-05-10
dbId	8870499
displayName	PLEKHA3,8 bind PI4P, ARF1
edited	[InstanceEdit:8870505] Jassal, Bijay, 2016-05-10
eventOf	[Pathway:R-HSA-1660499] Synthesis of PIPs at the plasma membrane - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-199971] ARF1 [Golgi membrane] [SimpleEntity:R-ALL-1806217] PI4P [Golgi membrane] [DefinedSet:R-HSA-8870506] PLEKHA3,8 [Golgi membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1675789] FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P [LiteratureReference:1675820] ARF mediates recruitment of PtdIns-4-OH kinase-beta and stimulates synthesis of PtdIns(4,5)P2 on the Golgi complex
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	PLEKHA3,8 bind PI4P, ARF1
orthologousEvent	[Reaction:R-PFA-8870499] PLEKHA3,8 bind PI4P, ARF1 - Plasmodium falciparum [Reaction:R-SCE-8870499] PLEKHA3,8 bind PI4P, ARF1 - Saccharomyces cerevisiae [Reaction:R-DDI-8870499] PLEKHA3,8 bind PI4P, ARF1 - Dictyostelium discoideum [Reaction:R-CEL-8870499] PLEKHA3,8 bind PI4P, ARF1 - Caenorhabditis elegans [Reaction:R-DME-8870499] PLEKHA3,8 bind PI4P, ARF1 - Drosophila melanogaster [Reaction:R-XTR-8870499] PLEKHA3,8 bind PI4P, ARF1 - Xenopus tropicalis [Reaction:R-DRE-8870499] PLEKHA3,8 bind PI4P, ARF1 - Danio rerio [Reaction:R-SSC-8870499] PLEKHA3,8 bind PI4P, ARF1 - Sus scrofa [Reaction:R-BTA-8870499] PLEKHA3,8 bind PI4P, ARF1 - Bos taurus [Reaction:R-CFA-8870499] PLEKHA3,8 bind PI4P, ARF1 - Canis familiaris [Reaction:R-RNO-8870499] PLEKHA3,8 bind PI4P, ARF1 - Rattus norvegicus [Reaction:R-MMU-8870499] PLEKHA3,8 bind PI4P, ARF1 - Mus musculus
output	[Complex:R-HSA-8870493] ARF1:PLEKHA3,8:PI4P [Golgi membrane]
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2016-09-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8879141] D'Eustachio, Peter, 2016-07-15 [InstanceEdit:9963238] Hill, David P, 2025-08-13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8870499
summation	[Summation:8870503] Proteins with the plekstrin homology (PH) domain are able to...
updateTrackers	[UpdateTracker:9964596] Update Tracker - [Reaction:8870499] PLEKHA3,8 bind PI4P, ARF1 - v94:[removeCatalystActivity]

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(updatedInstance)	[UpdateTracker:9964596] Update Tracker - [Reaction:8870499] PLEKHA3,8 bind PI4P, ARF1 - v94:[removeCatalystActivity]
(hasEvent)	[Pathway:R-HSA-1660499] Synthesis of PIPs at the plasma membrane