Reactome | Lysosomal oligosaccharide catabolism

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Lysosomal oligosaccharide catabolism Show undefined attributes

authored	[InstanceEdit:8853384] Jassal, Bijay, 2016-01-22
created	[InstanceEdit:8853384] Jassal, Bijay, 2016-01-22
dbId	8853383
displayName	Lysosomal oligosaccharide catabolism
edited	[InstanceEdit:8853384] Jassal, Bijay, 2016-01-22
eventOf	[Pathway:R-HSA-71387] Metabolism of carbohydrates and carbohydrate derivatives - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:25738] oligosaccharide catabolic process
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-HSA-6799545] MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 - Homo sapiens [BlackBoxEvent:R-HSA-8853391] GlcNAc (Man)5 translocates from cytosol to lysosomal lumen - Homo sapiens [Reaction:R-HSA-8853686] MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 - Homo sapiens [Reaction:R-HSA-6799581] MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man - Homo sapiens [Reaction:R-HSA-8853710] MANBA hydrolyses GlcNAc:Man - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8853721] Cytosolic-free oligosaccharides are predominantly generated by the degradation of dolichol-linked oligosaccharides in mammalian cells [LiteratureReference:2046194] Lysosomal degradation of Asn-linked glycoproteins [LiteratureReference:2046141] Lysosomal metabolism of glycoproteins
maxDepth	2
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	Lysosomal oligosaccharide catabolism
orthologousEvent	[Pathway:R-DRE-8853383] Lysosomal oligosaccharide catabolism - Danio rerio [Pathway:R-DDI-8853383] Lysosomal oligosaccharide catabolism - Dictyostelium discoideum [Pathway:R-SCE-8853383] Lysosomal oligosaccharide catabolism - Saccharomyces cerevisiae [Pathway:R-SPO-8853383] Lysosomal oligosaccharide catabolism - Schizosaccharomyces pombe [Pathway:R-XTR-8853383] Lysosomal oligosaccharide catabolism - Xenopus tropicalis [Pathway:R-CFA-8853383] Lysosomal oligosaccharide catabolism - Canis familiaris [Pathway:R-RNO-8853383] Lysosomal oligosaccharide catabolism - Rattus norvegicus [Pathway:R-MMU-8853383] Lysosomal oligosaccharide catabolism - Mus musculus [Pathway:R-SSC-8853383] Lysosomal oligosaccharide catabolism - Sus scrofa [Pathway:R-CEL-8853383] Lysosomal oligosaccharide catabolism - Caenorhabditis elegans [Pathway:R-DME-8853383] Lysosomal oligosaccharide catabolism - Drosophila melanogaster [Pathway:R-GGA-8853383] Lysosomal oligosaccharide catabolism - Gallus gallus [Pathway:R-BTA-8853383] Lysosomal oligosaccharide catabolism - Bos taurus
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8854020] D'Eustachio, Peter, 2016-01-26
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-8853383
summation	[Summation:8853720] N-Glycosylation is one of the most common co- and posttransl...

Referrals

(hasEvent)	[Pathway:R-HSA-71387] Metabolism of carbohydrates and carbohydrate derivatives
(hasEncapsulatedEvent)	[Pathway:R-HSA-446203] Asparagine N-linked glycosylation

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