Reactome | p-Y FGFR3 fusion dimers [plasma membrane]

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p-Y FGFR3 fusion dimers [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:8853230] Rothfels, Karen, 2016-01-21
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	8853232
disease	[Disease:1500689] cancer
displayName	p-Y FGFR3 fusion dimers [plasma membrane]
hasMember	[Complex:R-HSA-8853202] p-4Y FGFR3(23-758)-TACC3(549-838) dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-8853205] p-4Y FGFR3(23-758)-TACC3(649-838) dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-8853206] p-4Y FGFR3(23-760)-BAIAP2L1(18-522) dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-8853208] p-4Y FGFR3(23-760)-TACC3(612-838) dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-8853211] p-4Y FGFR3(23-760)-TACC3(647-838) dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-8853212] p-4Y FGFR3(23-793)-TACC3(143-838) dimer [plasma membrane] - Homo sapiens
inDisease	true
literatureReference	[LiteratureReference:8852962] Identification of recurrent FGFR3-TACC3 fusion oncogenes from lung adenocarcinoma [LiteratureReference:8852972] Identification of targetable FGFR gene fusions in diverse cancers [LiteratureReference:8853053] Transforming fusions of FGFR and TACC genes in human glioblastoma
maxDepth	3
memberOf	[DefinedSet:R-HSA-9753847] Activated FGFR3 point, translocation and fusion mutants [plasma membrane] - Homo sapiens
name	p-Y FGFR3 fusion dimers
producedByEvent	[Reaction:R-HSA-8853309] Autocatalytic phosphorylation of FGFR3 fusions - Homo sapiens
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-8853232
updateTrackers	[UpdateTracker:9965067] Update Tracker - [DefinedSet:8853232] p-Y FGFR3 fusion dimers [plasma membrane] - v94:[updateContainedMemberOrCandidate] [UpdateTracker:9895986] Update Tracker - [DefinedSet:8853232] p-Y FGFR3 fusion dimers [plasma membrane] - v60:[updateContainedMemberOrCandidate]

Referrals

(updatedInstance)	[UpdateTracker:9965067] Update Tracker - [DefinedSet:8853232] p-Y FGFR3 fusion dimers [plasma membrane] - v94:[updateContainedMemberOrCandidate] [UpdateTracker:9895986] Update Tracker - [DefinedSet:8853232] p-Y FGFR3 fusion dimers [plasma membrane] - v60:[updateContainedMemberOrCandidate]
(output)	[Reaction:R-HSA-8853309] Autocatalytic phosphorylation of FGFR3 fusions
(hasMember)	[DefinedSet:R-HSA-9753847] Activated FGFR3 point, translocation and fusion mutants [plasma membrane]

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