Reactome | FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-8853199] FGFR3(23-760)-TACC3(647-838) dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-8853199] FGFR3(23-760)-TACC3(647-838) dimer [plasma membrane] - Homo sapiens
created	[InstanceEdit:8853143] Rothfels, Karen, 2016-01-21
crossReference	[DatabaseIdentifier:12021028] Mondo:0004986
dbId	8853127
disease	[Disease:1493885] bladder carcinoma
displayName	FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane]
endCoordinate	793
hasModifiedResidue	[FragmentInsertionModification:8853102] Insertion of residues 647 to 838 at 761 from UniProt:Q9Y6A5 TACC3
inDisease	true
literatureReference	[LiteratureReference:8852972] Identification of targetable FGFR gene fusions in diverse cancers [LiteratureReference:8852986] Oncogenic FGFR3 gene fusions in bladder cancer
maxDepth	1
memberOf	[DefinedSet:R-HSA-8853269] FGFR3 fusions [plasma membrane] - Homo sapiens
name	FGFR3(23-760)-TACC3(647-838) fusion
referenceEntity	[ReferenceGeneProduct:uniprot:P22607] UniProt:P22607 FGFR3
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-8853127
startCoordinate	23

(hasComponent)	[Complex:R-HSA-8853199] FGFR3(23-760)-TACC3(647-838) dimer [plasma membrane]
(hasMember)	[DefinedSet:R-HSA-8853269] FGFR3 fusions [plasma membrane]

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