Reactome | FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-8853191] FGFR3(23-758)-TACC3(549-838) dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-8853191] FGFR3(23-758)-TACC3(549-838) dimer [plasma membrane] - Homo sapiens
created	[InstanceEdit:8853143] Rothfels, Karen, 2016-01-21
crossReference	[DatabaseIdentifier:12020790] Mondo:0018177 [DatabaseIdentifier:8853140] COSMIC:COSF1354
dbId	8853124
disease	[Disease:1247632] glioblastoma
displayName	FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane]
endCoordinate	758
hasModifiedResidue	[FragmentInsertionModification:8853116] Insertion of residues 549 to 838 at 759 from UniProt:Q9Y6A5 TACC3
inDisease	true
literatureReference	[LiteratureReference:8853053] Transforming fusions of FGFR and TACC genes in human glioblastoma
maxDepth	1
memberOf	[DefinedSet:R-HSA-8853269] FGFR3 fusions [plasma membrane] - Homo sapiens
modified	[InstanceEdit:9962055] Matthews, Lisa, 2025-07-30
name	FGFR3(23-758)-TACC3(549-838) fusion
referenceEntity	[ReferenceGeneProduct:uniprot:P22607] UniProt:P22607 FGFR3
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-8853124
startCoordinate	23
updateTrackers	[UpdateTracker:9964889] Update Tracker - [EntityWithAccessionedSequence:8853124] FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane] - v94:[add_removeDisease]

(updatedInstance)	[UpdateTracker:9964889] Update Tracker - [EntityWithAccessionedSequence:8853124] FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane] - v94:[add_removeDisease]
(hasComponent)	[Complex:R-HSA-8853191] FGFR3(23-758)-TACC3(549-838) dimer [plasma membrane]
(hasMember)	[DefinedSet:R-HSA-8853269] FGFR3 fusions [plasma membrane]

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