Reactome | FGFR2(22-768)-BICC1(80-974) fusion [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-8853186] FGFR2(22-768)-BICC1(80-974) fusion dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-8853186] FGFR2(22-768)-BICC1(80-974) fusion dimer [plasma membrane] - Homo sapiens
created	[InstanceEdit:8853143] Rothfels, Karen, 2016-01-21
crossReference	[DatabaseIdentifier:12021118] Mondo:0019087
dbId	8853123
disease	[Disease:8853118] cholangiocarcinoma
displayName	FGFR2(22-768)-BICC1(80-974) fusion [plasma membrane]
endCoordinate	768
hasModifiedResidue	[FragmentInsertionModification:8853108] Insertion of residues 80 to 974 at 769 from UniProt:Q9H694 BICC1
inDisease	true
literatureReference	[LiteratureReference:8852972] Identification of targetable FGFR gene fusions in diverse cancers [LiteratureReference:8852945] Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma
maxDepth	1
memberOf	[CandidateSet:R-HSA-8853265] FGFR2 fusions [plasma membrane] - Homo sapiens
name	FGFR2(22-768)-BICC1(80-974) fusion
referenceEntity	[ReferenceGeneProduct:uniprot:P21802] UniProt:P21802 FGFR2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-8853123
startCoordinate	22

(hasComponent)	[Complex:R-HSA-8853186] FGFR2(22-768)-BICC1(80-974) fusion dimer [plasma membrane]
(hasMember)	[CandidateSet:R-HSA-8853265] FGFR2 fusions [plasma membrane]

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