Reactome | Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends

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Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends Show undefined attributes

authored	[InstanceEdit:8852278] Orlic-Milacic, Marija, 2016-01-15
catalystActivity	[CatalystActivity:8853809] protein serine/threonine kinase activity of Mitotic kinase [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:8852310] Orlic-Milacic, Marija, 2016-01-15
dbId	8852306
displayName	Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends
edited	[InstanceEdit:8852278] Orlic-Milacic, Marija, 2016-01-15
eventOf	[Pathway:R-HSA-8852276] The role of GTSE1 in G2/M progression after G2 checkpoint - Homo sapiens
input	2 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-HSA-8852295] GTSE1:MAPRE1:microtubule plus end [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8852282] GTSE1 is a microtubule plus-end tracking protein that regulates EB1-dependent cell migration
maxDepth	1
modified	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
name	Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends
orthologousEvent	[Reaction:R-XTR-8852306] Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends - Xenopus tropicalis [Reaction:R-SSC-8852306] Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends - Sus scrofa [Reaction:R-CFA-8852306] Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends - Canis familiaris [Reaction:R-RNO-8852306] Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends - Rattus norvegicus [Reaction:R-MMU-8852306] Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends - Mus musculus
output	2 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-HSA-8852300] MAPRE1:microtubule plus end [cytosol] [EntityWithAccessionedSequence:R-HSA-8852308] p-T513,T526-GTSE1 [cytosol]
precedingEvent	[Reaction:R-HSA-8852298] GTSE1 binds MAPRE1 (EB1) at microtubule plus ends - Homo sapiens [Reaction:R-HSA-170161] Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B - Homo sapiens
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8855167] Bird, Alexander W, 2016-01-22
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8852306
summation	[Summation:8852311] Starting in mitotic prometaphase, GTSE1 becomes phosphorylat...

Referrals

(hasEvent)	[Pathway:R-HSA-8852276] The role of GTSE1 in G2/M progression after G2 checkpoint
(precedingEvent)	[NegativePrecedingEvent:9764037] Futile Cycle: Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends

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