Reactome | PLA2s hydrolyze phospholipids at the Golgi membrane

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PLA2s hydrolyze phospholipids at the Golgi membrane Show undefined attributes

authored	[InstanceEdit:6809025] Rothfels, Karen, 2015-11-09
catalystActivity	[CatalystActivity:8848480] phospholipase A2 activity of cPLA2s [cytosol]
category	transition
compartment	[Compartment:20699] Golgi membrane
created	[InstanceEdit:8848482] Rothfels, Karen, 2015-12-08
crossReference	[DatabaseIdentifier:11880929] Rhea:15801
dbId	8848484
displayName	PLA2s hydrolyze phospholipids at the Golgi membrane
edited	[InstanceEdit:6809025] Rothfels, Karen, 2015-11-09
eventOf	[Pathway:R-HSA-6811436] COPI-independent Golgi-to-ER retrograde traffic - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-429785] PC [Golgi membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8848559] The expanding superfamily of phospholipase A(2) enzymes: classification and characterization [LiteratureReference:8848562] Phospholipase A2 enzymes [LiteratureReference:8849278] Evidence that phospholipase A2 activity is required for Golgi complex and trans Golgi network membrane tubulation [LiteratureReference:8849295] Membrane tubule-mediated reassembly and maintenance of the Golgi complex is disrupted by phospholipase A2 antagonists [LiteratureReference:8848553] A PLA1-2 punch regulates the Golgi complex [LiteratureReference:8849691] Group IV phospholipase A(2)alpha controls the formation of inter-cisternal continuities involved in intra-Golgi transport [LiteratureReference:8849707] Synchronous intra-Golgi transport induces the release of Ca2+ from the Golgi apparatus [LiteratureReference:8849680] A traffic-activated Golgi-based signalling circuit coordinates the secretory pathway
modified	[InstanceEdit:11879863] Wright, Adam, 2024-03-11
name	PLA2s hydrolyze phospholipids at the Golgi membrane
orthologousEvent	[Reaction:R-SCE-8848484] PLA2s hydrolyze phospholipids at the Golgi membrane - Saccharomyces cerevisiae [Reaction:R-SPO-8848484] PLA2s hydrolyze phospholipids at the Golgi membrane - Schizosaccharomyces pombe [Reaction:R-CEL-8848484] PLA2s hydrolyze phospholipids at the Golgi membrane - Caenorhabditis elegans [Reaction:R-DME-8848484] PLA2s hydrolyze phospholipids at the Golgi membrane - Drosophila melanogaster [Reaction:R-GGA-8848484] PLA2s hydrolyze phospholipids at the Golgi membrane - Gallus gallus [Reaction:R-XTR-8848484] PLA2s hydrolyze phospholipids at the Golgi membrane - Xenopus tropicalis [Reaction:R-DRE-8848484] PLA2s hydrolyze phospholipids at the Golgi membrane - Danio rerio [Reaction:R-SSC-8848484] PLA2s hydrolyze phospholipids at the Golgi membrane - Sus scrofa [Reaction:R-BTA-8848484] PLA2s hydrolyze phospholipids at the Golgi membrane - Bos taurus [Reaction:R-CFA-8848484] PLA2s hydrolyze phospholipids at the Golgi membrane - Canis familiaris [Reaction:R-RNO-8848484] PLA2s hydrolyze phospholipids at the Golgi membrane - Rattus norvegicus [Reaction:R-MMU-8848484] PLA2s hydrolyze phospholipids at the Golgi membrane - Mus musculus
output	[SimpleEntity:R-ALL-8848483] 2-lysophosphatidylcholine [Golgi membrane] [SimpleEntity:R-ALL-6814303] fatty acid [cytosol]
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8855182] Gillespie, Marc E, 2016-02-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8848484
summation	[Summation:8848555] Phospholipase A (PLA2) hydrolyzes the sn-2 position of phosp...

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[Pathway:R-HSA-6811436] COPI-independent Golgi-to-ER retrograde traffic

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