Reactome | IDH1 R132H mutant [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-880043] IDH1 R132H dimer [cytosol] - Homo sapiens [Complex:R-HSA-880043] IDH1 R132H dimer [cytosol] - Homo sapiens
created	[InstanceEdit:880051] D'Eustachio, P, 2010-06-25
crossReference	[DatabaseIdentifier:12020790] Mondo:0018177 [DatabaseIdentifier:2203429] COSMIC:COSV61615239 [DatabaseIdentifier:2203427] COSMIC:COSM41291
dbId	880015
disease	[Disease:1247632] glioblastoma
displayName	IDH1 R132H mutant [cytosol]
endCoordinate	414
hasModifiedResidue	[ReplacedResidue:880049] L-arginine 132 replaced with L-histidine
inDisease	true
maxDepth	1
modified	[InstanceEdit:2565931] Jassal, B, 2012-11-08
name	IDH1 R132H mutant Isocitrate dehydrogenase (NADP) cytoplasmic R132H
referenceEntity	[ReferenceGeneProduct:uniprot:O75874] UniProt:O75874 IDH1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-880015
startCoordinate	1
updateTrackers	[UpdateTracker:9871764] Update Tracker - [EntityWithAccessionedSequence:880015] IDH1 R132H mutant [cytosol] - v41:[addDisease, modifyEndCoordinate, modifyName] [UpdateTracker:9873774] Update Tracker - [EntityWithAccessionedSequence:880015] IDH1 R132H mutant [cytosol] - v43:[modifyName]

(updatedInstance)	[UpdateTracker:9871764] Update Tracker - [EntityWithAccessionedSequence:880015] IDH1 R132H mutant [cytosol] - v41:[addDisease, modifyEndCoordinate, modifyName] [UpdateTracker:9873774] Update Tracker - [EntityWithAccessionedSequence:880015] IDH1 R132H mutant [cytosol] - v43:[modifyName]
(hasComponent)	[Complex:R-HSA-880043] IDH1 R132H dimer [cytosol]

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