Reactome | SLC27A1,4,6 transport LCFAs from extracellular region to cytosol

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SLC27A1,4,6 transport LCFAs from extracellular region to cytosol Show undefined attributes

authored	[InstanceEdit:879538] Jassal, Bijay, 2010-06-18
catalystActivity	[CatalystActivity:879525] fatty acid transmembrane transporter activity of SLC27A1,4,6 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:879538] Jassal, Bijay, 2010-06-18
dbId	879585
diseaseReaction	[FailedReaction:R-HSA-5627891] Defective SLC27A4 does not transport LCFAs from extracellular region to cytosol - Homo sapiens
displayName	SLC27A1,4,6 transport LCFAs from extracellular region to cytosol
edited	[InstanceEdit:879538] Jassal, Bijay, 2010-06-18
eventOf	[Pathway:R-HSA-804914] Transport of fatty acids - Homo sapiens
input	[CandidateSet:R-ALL-879559] LCFAs [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:879511] FATP1 channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells [LiteratureReference:879619] Tissue distribution and cDNA cloning of a human fatty acid transport protein (hsFATP4) [LiteratureReference:879591] Identification of the major intestinal fatty acid transport protein [LiteratureReference:879539] Characterization of a heart-specific fatty acid transport protein
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	SLC27A1,4,6 transport LCFAs from extracellular region to cytosol
orthologousEvent	[Reaction:R-CEL-879585] SLC27A1,4,6 transport LCFAs from extracellular region to cytosol - Caenorhabditis elegans [Reaction:R-DME-879585] SLC27A1,4,6 transport LCFAs from extracellular region to cytosol - Drosophila melanogaster [Reaction:R-GGA-879585] SLC27A1,4,6 transport LCFAs from extracellular region to cytosol - Gallus gallus [Reaction:R-XTR-879585] SLC27A1,4,6 transport LCFAs from extracellular region to cytosol - Xenopus tropicalis [Reaction:R-DRE-879585] SLC27A1,4,6 transport LCFAs from extracellular region to cytosol - Danio rerio [Reaction:R-SSC-879585] SLC27A1,4,6 transport LCFAs from extracellular region to cytosol - Sus scrofa [Reaction:R-BTA-879585] SLC27A1,4,6 transport LCFAs from extracellular region to cytosol - Bos taurus [Reaction:R-CFA-879585] SLC27A1,4,6 transport LCFAs from extracellular region to cytosol - Canis familiaris [Reaction:R-RNO-879585] SLC27A1,4,6 transport LCFAs from extracellular region to cytosol - Rattus norvegicus [Reaction:R-MMU-879585] SLC27A1,4,6 transport LCFAs from extracellular region to cytosol - Mus musculus
output	[CandidateSet:R-ALL-879544] LCFAs [cytosol]
releaseDate	2010-09-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:909534] He, L, 2010-07-07
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-879585
summation	[Summation:879564] The SLC27 gene family code for fatty acid transporter protei...
systematicName	SLC27A1,4,6 transport LCFAs from extracellular region to cytosol
updateTrackers	[UpdateTracker:9785913] Update Tracker - [Reaction:879585] SLC27A1,4,6 transport LCFAs from extracellular region to cytosol - v51:[modifyText] [UpdateTracker:9787386] Update Tracker - [Reaction:879585] SLC27A1,4,6 transport LCFAs from extracellular region to cytosol - v45:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9785913] Update Tracker - [Reaction:879585] SLC27A1,4,6 transport LCFAs from extracellular region to cytosol - v51:[modifyText] [UpdateTracker:9787386] Update Tracker - [Reaction:879585] SLC27A1,4,6 transport LCFAs from extracellular region to cytosol - v45:[modifyText]
(normalReaction)	[FailedReaction:R-HSA-5627891] Defective SLC27A4 does not transport LCFAs from extracellular region to cytosol
(hasEvent)	[Pathway:R-HSA-804914] Transport of fatty acids