Reactome | Formation of cap binding complex (CBC)

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Formation of cap binding complex (CBC) Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:77054] Buratowski, S, 2003-10-15 15:18:41
dbId	77094
displayName	Formation of cap binding complex (CBC)
eventOf	[Pathway:R-HSA-72086] mRNA Capping - Homo sapiens
followingEvent	[Reaction:R-HSA-77095] Recognition and binding of the mRNA cap by the cap-binding complex - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-51469] NCBP1 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-51463] NCBP2 [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8984161] Mutually Exclusive CBC-Containing Complexes Contribute to RNA Fate [LiteratureReference:8984100] Cotranscriptional spliceosome assembly occurs in a stepwise fashion and requires the cap binding complex [LiteratureReference:8984167] NELF interacts with CBC and participates in 3' end processing of replication-dependent histone mRNAs [LiteratureReference:8984154] RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	Formation of cap binding complex (CBC)
orthologousEvent	[Reaction:R-SCE-77094] Formation of cap binding complex (CBC) - Saccharomyces cerevisiae [Reaction:R-SPO-77094] Formation of cap binding complex (CBC) - Schizosaccharomyces pombe [Reaction:R-DDI-77094] Formation of cap binding complex (CBC) - Dictyostelium discoideum [Reaction:R-CEL-77094] Formation of cap binding complex (CBC) - Caenorhabditis elegans [Reaction:R-DME-77094] Formation of cap binding complex (CBC) - Drosophila melanogaster [Reaction:R-GGA-77094] Formation of cap binding complex (CBC) - Gallus gallus [Reaction:R-XTR-77094] Formation of cap binding complex (CBC) - Xenopus tropicalis [Reaction:R-SSC-77094] Formation of cap binding complex (CBC) - Sus scrofa [Reaction:R-BTA-77094] Formation of cap binding complex (CBC) - Bos taurus [Reaction:R-CFA-77094] Formation of cap binding complex (CBC) - Canis familiaris [Reaction:R-RNO-77094] Formation of cap binding complex (CBC) - Rattus norvegicus [Reaction:R-MMU-77094] Formation of cap binding complex (CBC) - Mus musculus
output	[Complex:R-HSA-77088] Cap Binding Complex (CBC) [nucleoplasm]
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-77094
summation	[Summation:178768] At the beginning of this reaction, 1 molecule of 'CBP80', an...
updateTrackers	[UpdateTracker:9781466] Update Tracker - [Reaction:77094] Formation of cap binding complex (CBC) - v61:[addLiteratureReference, modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9781466] Update Tracker - [Reaction:77094] Formation of cap binding complex (CBC) - v61:[addLiteratureReference, modifyText]
(hasEvent)	[Pathway:R-HSA-72086] mRNA Capping
(precedingEvent)	[Reaction:R-HSA-77095] Recognition and binding of the mRNA cap by the cap-binding complex

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