Reactome | Formation of cap binding complex (CBC)

Formation of cap binding complex (CBC)

Stable Identifier

R-HSA-77094

Type

Reaction [binding]

Species

Homo sapiens

Compartment

nucleoplasm

ReviewStatus

5/5

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At the beginning of this reaction, 1 molecule of 'CBP80', and 1 molecule of 'CBP20' are present. At the end of this reaction, 1 molecule of 'Cap Binding Complex (CBC)' is present (Glover-Cutter et al., 2008, Görnemann et al., 2005, Narita et al., 2007). This reaction takes place in the nucleus.

Literature References

PubMed ID	Title	Journal	Year
17499042	NELF interacts with CBC and participates in 3' end processing of replication-dependent histone mRNAs Narita, T, Yung, TM, Yamamoto, J, Tsuboi, Y, Tanabe, H, Tanaka, K, Yamaguchi, Y, Handa, H	Mol. Cell	2007
15989964	Cotranscriptional spliceosome assembly occurs in a stepwise fashion and requires the cap binding complex Görnemann, J, Kotovic, KM, Hujer, K, Neugebauer, KM	Mol. Cell	2005
28297668	Mutually Exclusive CBC-Containing Complexes Contribute to RNA Fate Giacometti, S, Benbahouche, NE, Domanski, M, Robert, MC, Meola, N, Lubas, M, Bukenborg, J, Andersen, JS, Schulze, WM, Verheggen, C, Kudla, G, Jensen, TH, Bertrand, E	Cell Rep	2017
18157150	RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes Glover-Cutter, K, Kim, S, Espinosa, J, Bentley, DL	Nat. Struct. Mol. Biol.	2008