Reactome | 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate

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1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate Show undefined attributes

authored	[InstanceEdit:76232] Gopinathrao, G, 2003-10-02 00:00:00
catalystActivity	[CatalystActivity:549156] phosphatidate phosphatase activity of LPIN1,2,3 [endoplasmic reticulum membrane]
catalystActivityReference	[CatalystActivityReference:9643205] phosphatidate phosphatase activity of LPIN1,2,3 [endoplasmic reticulum membrane] Temporal and spatial regulation of the phosphatidate phosphatases lipin 1 and 2
category	transition
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:75111] Gopinathrao, G, 2003-09-07 15:00:00
crossReference	[DatabaseIdentifier:12668372] RHEA:27430
dbId	75899
deleted	[Deleted:428113] Deletion of instance: 76134 [Deleted:428111] Deletion of instance: 76130 [Deleted:428114] Deletion of instance: 75898
displayName	1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate
eventOf	[Pathway:R-HSA-75109] Triglyceride biosynthesis - Homo sapiens
followingEvent	[Reaction:R-HSA-75900] 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] - Homo sapiens [Reaction:R-HSA-549192] 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] - Homo sapiens
input	[SimpleEntity:R-ALL-76108] 1,2-daG3P [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:549163] Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns [LiteratureReference:549166] Temporal and spatial regulation of the phosphatidate phosphatases lipin 1 and 2
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate Conversion of Phosphatidic Acid to Diacylglycerol
orthologousEvent	[Reaction:R-PFA-75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate - Plasmodium falciparum [Reaction:R-SCE-75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate - Saccharomyces cerevisiae [Reaction:R-SPO-75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate - Schizosaccharomyces pombe [Reaction:R-DDI-75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate - Dictyostelium discoideum [Reaction:R-CEL-75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate - Caenorhabditis elegans [Reaction:R-DME-75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate - Drosophila melanogaster [Reaction:R-GGA-75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate - Gallus gallus [Reaction:R-XTR-75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate - Xenopus tropicalis [Reaction:R-DRE-75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate - Danio rerio [Reaction:R-SSC-75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate - Sus scrofa [Reaction:R-BTA-75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate - Bos taurus [Reaction:R-CFA-75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate - Canis familiaris [Reaction:R-RNO-75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate - Rattus norvegicus [Reaction:R-MMU-75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate - Mus musculus
output	[SimpleEntity:R-ALL-76103] DAG [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol]
precedingEvent	[Reaction:R-HSA-75885] 1-acyl LPA is acylated to PA by AGPAT (LPAAT) - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-75899
summation	[Summation:76253] Lipin proteins LPIN1, 2, and 3, associated with the endoplas...
updateTrackers	[UpdateTracker:9790695] Update Tracker - [Reaction:75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate - v33:[add_removeCatalystActivity, add_removeLiteratureReference, modifyText] [UpdateTracker:9781589] Update Tracker - [Reaction:75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate - v60:[addOutput]

Referrals

(updatedInstance)	[UpdateTracker:9790695] Update Tracker - [Reaction:75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate - v33:[add_removeCatalystActivity, add_removeLiteratureReference, modifyText] [UpdateTracker:9781589] Update Tracker - [Reaction:75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate - v60:[addOutput]
(replacementInstances)	[Deleted:428113] Deletion of instance: 76134 [Deleted:428111] Deletion of instance: 76130 [Deleted:428114] Deletion of instance: 75898
(precedingEvent)	[Reaction:R-HSA-75900] 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] [Reaction:R-HSA-549192] 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2]
(hasEvent)	[Pathway:R-HSA-75109] Triglyceride biosynthesis

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