Reactome | 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2]

Schema > Reaction > Entries

1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] Show undefined attributes

catalystActivity	[CatalystActivity:549191] diacylglycerol O-acyltransferase activity of DGAT2 [endoplasmic reticulum membrane]
catalystActivityReference	[CatalystActivityReference:9643744] diacylglycerol O-acyltransferase activity of DGAT2 [endoplasmic reticulum membrane] Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members
category	transition
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:549172] D'Eustachio, P, 2010-03-17
dbId	549192
displayName	1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2]
eventOf	[Pathway:R-HSA-75109] Triglyceride biosynthesis - Homo sapiens
input	[SimpleEntity:R-ALL-76103] DAG [cytosol] [SimpleEntity:R-ALL-75967] FACoA [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:549174] Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members [LiteratureReference:549189] A novel diacylglycerol acyltransferase (DGAT2) is decreased in human psoriatic skin and increased in diabetic mice
modified	[InstanceEdit:10901498] Wright, Adam, 2024-03-08
name	1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] Conversion of Diacylglycerol to Triacylglycerol [DGAT2]
orthologousEvent	[Reaction:R-SCE-549192] 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] - Saccharomyces cerevisiae [Reaction:R-SPO-549192] 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] - Schizosaccharomyces pombe [Reaction:R-DDI-549192] 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] - Dictyostelium discoideum [Reaction:R-CEL-549192] 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] - Caenorhabditis elegans [Reaction:R-DME-549192] 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] - Drosophila melanogaster [Reaction:R-GGA-549192] 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] - Gallus gallus [Reaction:R-XTR-549192] 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] - Xenopus tropicalis [Reaction:R-DRE-549192] 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] - Danio rerio [Reaction:R-SSC-549192] 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] - Sus scrofa [Reaction:R-CFA-549192] 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] - Canis familiaris [Reaction:R-RNO-549192] 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] - Rattus norvegicus [Reaction:R-MMU-549192] 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] - Mus musculus
output	[SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [SimpleEntity:R-ALL-549167] TAG [cytosol]
precedingEvent	[Reaction:R-HSA-75899] 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate - Homo sapiens
releaseDate	2009-04-01
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-549192
summation	[Summation:549194] Diacylglycerol O-acyltransferase 1 (DGAT2) associated with t...

Referrals

(hasEvent)

[Pathway:R-HSA-75109] Triglyceride biosynthesis