Reactome | Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane]

Schema > Complex > Entries

Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-749454] The Ligand:GPCR:Gi complex dissociates - Homo sapiens
created	[InstanceEdit:749449] Jupe, S, 2010-05-18
dbId	749445
displayName	Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane]
hasComponent	[Complex:R-HSA-392168] Heterotrimeric G-protein Gi (active) [plasma membrane] [DefinedSet:R-HSA-380091] Ligand:GPCR complexes that activate Gi [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - Mus musculus [Complex:R-RNO-749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - Rattus norvegicus [Complex:R-CFA-749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - Canis familiaris [Complex:R-BTA-749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - Bos taurus [Complex:R-SSC-749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - Sus scrofa [Complex:R-DRE-749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - Danio rerio [Complex:R-XTR-749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - Gallus gallus [Complex:R-DME-749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - Drosophila melanogaster [Complex:R-CEL-749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - Caenorhabditis elegans [Complex:R-DDI-749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - Dictyostelium discoideum
isChimeric	false
maxDepth	6
modified	[InstanceEdit:749459] Jupe, S, 2010-05-18
name	Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active)
producedByEvent	[Reaction:R-HSA-380073] Liganded Gi-activating GPCR acts as a GEF for Gi - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-749445
updateTrackers	[UpdateTracker:9888042] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v46:[updateContainedComponent] [UpdateTracker:9898200] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v63:[updateContainedComponent] [UpdateTracker:9895373] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v59:[updateContainedComponent] [UpdateTracker:9905141] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v83:[updateContainedComponent] [UpdateTracker:9895884] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v60:[updateContainedComponent] [UpdateTracker:9899516] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v66:[updateContainedComponent] [UpdateTracker:9869827] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v35:[updateContainedComponent] [UpdateTracker:9902339] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v77:[updateContainedComponent] [UpdateTracker:9901124] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v72:[updateContainedComponent] [UpdateTracker:9901544] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v74:[updateContainedComponent] [UpdateTracker:9873030] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v42:[updateContainedComponent] [UpdateTracker:9893649] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v56:[updateContainedComponent] [UpdateTracker:9939922] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v92:[updateContainedComponent] [UpdateTracker:9892978] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v54:[updateContainedComponent] [UpdateTracker:9899989] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v67:[updateContainedComponent] [UpdateTracker:9869596] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v34:[updateContainedComponent] [UpdateTracker:9880675] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v45:[updateContainedComponent] [UpdateTracker:9953881] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v93:[updateContainedComponent] [UpdateTracker:9899022] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v64:[updateContainedComponent] [UpdateTracker:9900790] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v70:[updateContainedComponent] [UpdateTracker:9892543] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v53:[updateContainedComponent] [UpdateTracker:9878081] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v44:[updateContainedComponent] [UpdateTracker:9872295] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v41:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9888042] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v46:[updateContainedComponent] [UpdateTracker:9898200] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v63:[updateContainedComponent] [UpdateTracker:9895373] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v59:[updateContainedComponent] [UpdateTracker:9905141] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v83:[updateContainedComponent] [UpdateTracker:9895884] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v60:[updateContainedComponent] [UpdateTracker:9899516] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v66:[updateContainedComponent] [UpdateTracker:9869827] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v35:[updateContainedComponent] [UpdateTracker:9902339] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v77:[updateContainedComponent] [UpdateTracker:9901124] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v72:[updateContainedComponent] [UpdateTracker:9901544] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v74:[updateContainedComponent] [UpdateTracker:9873030] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v42:[updateContainedComponent] [UpdateTracker:9893649] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v56:[updateContainedComponent] [UpdateTracker:9939922] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v92:[updateContainedComponent] [UpdateTracker:9892978] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v54:[updateContainedComponent] [UpdateTracker:9899989] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v67:[updateContainedComponent] [UpdateTracker:9869596] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v34:[updateContainedComponent] [UpdateTracker:9880675] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v45:[updateContainedComponent] [UpdateTracker:9953881] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v93:[updateContainedComponent] [UpdateTracker:9899022] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v64:[updateContainedComponent] [UpdateTracker:9900790] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v70:[updateContainedComponent] [UpdateTracker:9892543] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v53:[updateContainedComponent] [UpdateTracker:9878081] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v44:[updateContainedComponent] [UpdateTracker:9872295] Update Tracker - [Complex:749445] Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] - v41:[updateContainedComponent]
(output)	[Reaction:R-HSA-380073] Liganded Gi-activating GPCR acts as a GEF for Gi
(input)	[Reaction:R-HSA-749454] The Ligand:GPCR:Gi complex dissociates

© 2026 Reactome

Cite Us!