Reactome | Resynthesis of excised residue by POLB

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Resynthesis of excised residue by POLB Show undefined attributes

authored	[InstanceEdit:110327] Matthews, L, 2004-01-29 18:52:00
catalystActivity	[CatalystActivity:5649635] DNA-directed DNA polymerase activity of LIG3:XRCC1:POLB:SSB-gap-dsDNA [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:110175] Matthews, L, 2004-01-29 08:00:00
dbId	73932
displayName	Resynthesis of excised residue by POLB
edited	[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00 [InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
eventOf	[Pathway:R-HSA-110381] Resolution of AP sites via the single-nucleotide replacement pathway - Homo sapiens
followingEvent	[Reaction:R-HSA-73931] LIG3-mediated DNA ligation via the single-nucleotide replacement pathway - Homo sapiens
input	[SimpleEntity:R-ALL-30555] dNTP [nucleoplasm] [Complex:R-HSA-110339] LIG3:XRCC1:POLB:SSB-gap-dsDNA [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:111257] Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein.
maxDepth	1
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	Resynthesis of excised residue by POLB
orthologousEvent	[Reaction:R-DDI-73932] Resynthesis of excised residue by POLB - Dictyostelium discoideum [Reaction:R-XTR-73932] Resynthesis of excised residue by POLB - Xenopus tropicalis [Reaction:R-DRE-73932] Resynthesis of excised residue by POLB - Danio rerio [Reaction:R-SSC-73932] Resynthesis of excised residue by POLB - Sus scrofa [Reaction:R-BTA-73932] Resynthesis of excised residue by POLB - Bos taurus [Reaction:R-CFA-73932] Resynthesis of excised residue by POLB - Canis familiaris [Reaction:R-RNO-73932] Resynthesis of excised residue by POLB - Rattus norvegicus [Reaction:R-MMU-73932] Resynthesis of excised residue by POLB - Mus musculus
output	[Complex:R-HSA-110341] LIG3:XRCC1:POLB:SSB-dsDNA [nucleoplasm] [SimpleEntity:R-ALL-113541] PPi [nucleoplasm]
precedingEvent	[Reaction:R-HSA-110376] Recruitment of LIG3:XRCC1 complex to the site of repair by POLB - Homo sapiens
releaseDate	2004-03-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5673689] Borowiec, James, 2014-12-22
revised	[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-73932
summation	[Summation:110378] POLB (DNA polymerase beta) mediates DNA synthesis that fills...
updateTrackers	[UpdateTracker:9784888] Update Tracker - [Reaction:73932] Resynthesis of excised residue by POLB - v52:[add_removeCatalystActivity, modifyText] [UpdateTracker:9785700] Update Tracker - [Reaction:73932] Resynthesis of excised residue by POLB - v51:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9784888] Update Tracker - [Reaction:73932] Resynthesis of excised residue by POLB - v52:[add_removeCatalystActivity, modifyText] [UpdateTracker:9785700] Update Tracker - [Reaction:73932] Resynthesis of excised residue by POLB - v51:[modifyText]
(hasEvent)	[Pathway:R-HSA-110381] Resolution of AP sites via the single-nucleotide replacement pathway
(precedingEvent)	[Reaction:R-HSA-73931] LIG3-mediated DNA ligation via the single-nucleotide replacement pathway

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