Reactome | G2/M DNA replication checkpoint

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G2/M DNA replication checkpoint Show undefined attributes

created	[InstanceEdit:68869] Walworth, N, O'Donnell, M, 2003-06-05
crossReference	[DatabaseIdentifier:12819489] BioModels Database:BIOMD0000000939 [DatabaseIdentifier:12819439] BioModels Database:BIOMD0000000657 [DatabaseIdentifier:12819587] BioModels Database:BIOMD0000000723
dbId	69478
displayName	G2/M DNA replication checkpoint
eventOf	[Pathway:R-HSA-69481] G2/M Checkpoints - Homo sapiens
figure	[Figure:9689483] /figures/static/R-HSA-69478.svg
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-170055] Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes - Homo sapiens [Reaction:R-HSA-170070] Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2017-06-22
maxDepth	2
modified	[InstanceEdit:12819426] Weiser, Joel, 2026-02-23
name	G2/M DNA replication checkpoint
orthologousEvent	[Pathway:R-CEL-69478] G2/M DNA replication checkpoint - Caenorhabditis elegans [Pathway:R-DME-69478] G2/M DNA replication checkpoint - Drosophila melanogaster [Pathway:R-XTR-69478] G2/M DNA replication checkpoint - Xenopus tropicalis [Pathway:R-DRE-69478] G2/M DNA replication checkpoint - Danio rerio [Pathway:R-SSC-69478] G2/M DNA replication checkpoint - Sus scrofa [Pathway:R-BTA-69478] G2/M DNA replication checkpoint - Bos taurus [Pathway:R-CFA-69478] G2/M DNA replication checkpoint - Canis familiaris [Pathway:R-RNO-69478] G2/M DNA replication checkpoint - Rattus norvegicus [Pathway:R-MMU-69478] G2/M DNA replication checkpoint - Mus musculus
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-69478
summation	[Summation:69480] The G2/M DNA replication checkpoint ensures that mitosis is ...
updateTrackers	[UpdateTracker:9787052] Update Tracker - [Pathway:69478] G2/M DNA replication checkpoint - v46:[updateContainedRLE] [UpdateTracker:9792059] Update Tracker - [Pathway:69478] G2/M DNA replication checkpoint - v24:[modifyText, removeHasEvent] [UpdateTracker:9781158] Update Tracker - [Pathway:69478] G2/M DNA replication checkpoint - v61:[updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9787052] Update Tracker - [Pathway:69478] G2/M DNA replication checkpoint - v46:[updateContainedRLE] [UpdateTracker:9792059] Update Tracker - [Pathway:69478] G2/M DNA replication checkpoint - v24:[modifyText, removeHasEvent] [UpdateTracker:9781158] Update Tracker - [Pathway:69478] G2/M DNA replication checkpoint - v61:[updateContainedRLE]
(hasEvent)	[Pathway:R-HSA-69481] G2/M Checkpoints