Reactome | G2/M DNA replication checkpoint

Schema > Pathway > Entries

created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10329445
displayName	G2/M DNA replication checkpoint
eventOf	[Pathway:R-CFA-69481] G2/M Checkpoints - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CFA-170055] Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes - Canis familiaris [Reaction:R-CFA-170070] Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes - Canis familiaris
inferredFrom	[Pathway:R-HSA-69478] G2/M DNA replication checkpoint - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	G2/M DNA replication checkpoint
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-69478
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-69481] G2/M Checkpoints
(inferredTo)	[Pathway:R-HSA-69478] G2/M DNA replication checkpoint

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