Reactome | G1/S Transition

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G1/S Transition Show undefined attributes

created	[InstanceEdit:68869] Walworth, N, O'Donnell, M, 2003-06-05
dbId	69206
definition	Progression from G1 phase to S phase of the standard mitotic cell cycle.
displayName	G1/S Transition
doi	10.3180/REACT_1783.2
eventOf	[Pathway:R-HSA-453279] Mitotic G1 phase and G1/S transition - Homo sapiens
figure	[Figure:69207] /figures/CellCycle_5.jpg
followingEvent	[Pathway:R-HSA-69242] S Phase - Homo sapiens [Pathway:R-HSA-69190] DNA strand elongation - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:20667] G1/S transition of mitotic cell cycle
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-HSA-69202] Cyclin E associated events during G1/S transition - Homo sapiens [Pathway:R-HSA-69205] G1/S-Specific Transcription - Homo sapiens [Pathway:R-HSA-68962] Activation of the pre-replicative complex - Homo sapiens [Pathway:R-HSA-113510] E2F mediated regulation of DNA replication - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2021-12-08
maxDepth	4
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	G1/S Transition
orthologousEvent	[Pathway:R-DDI-69206] G1/S Transition - Dictyostelium discoideum [Pathway:R-SCE-69206] G1/S Transition - Saccharomyces cerevisiae [Pathway:R-XTR-69206] G1/S Transition - Xenopus tropicalis [Pathway:R-CEL-69206] G1/S Transition - Caenorhabditis elegans [Pathway:R-DME-69206] G1/S Transition - Drosophila melanogaster [Pathway:R-GGA-69206] G1/S Transition - Gallus gallus [Pathway:R-PFA-69206] G1/S Transition - Plasmodium falciparum [Pathway:R-SPO-69206] G1/S Transition - Schizosaccharomyces pombe [Pathway:R-DRE-69206] G1/S Transition - Danio rerio [Pathway:R-SSC-69206] G1/S Transition - Sus scrofa [Pathway:R-CFA-69206] G1/S Transition - Canis familiaris [Pathway:R-BTA-69206] G1/S Transition - Bos taurus [Pathway:R-RNO-69206] G1/S Transition - Rattus norvegicus [Pathway:R-MMU-69206] G1/S Transition - Mus musculus
precedingEvent	[Pathway:R-HSA-69236] G1 Phase - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-69206
summation	[Summation:69286] Cyclin E - Cdk2 complexes control the transition from G1 int...
updateTrackers	[UpdateTracker:9779261] Update Tracker - [Pathway:69206] G1/S Transition - v66:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9779360] Update Tracker - [Pathway:69206] G1/S Transition - v65:[updateIndirectRLE] [UpdateTracker:9792201] Update Tracker - [Pathway:69206] G1/S Transition - v22:[updateIndirectRLE] [UpdateTracker:9786724] Update Tracker - [Pathway:69206] G1/S Transition - v48:[updateContainedPathway] [UpdateTracker:9775445] Update Tracker - [Pathway:69206] G1/S Transition - v79:[updateIndirectRLE] [UpdateTracker:9778368] Update Tracker - [Pathway:69206] G1/S Transition - v68:[updateContainedPathway] [UpdateTracker:9780352] Update Tracker - [Pathway:69206] G1/S Transition - v63:[updateContainedPathway] [UpdateTracker:9787171] Update Tracker - [Pathway:69206] G1/S Transition - v46:[updateIndirectRLE] [UpdateTracker:9775703] Update Tracker - [Pathway:69206] G1/S Transition - v78:[updateIndirectRLE] [UpdateTracker:9791954] Update Tracker - [Pathway:69206] G1/S Transition - v24:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9781551] Update Tracker - [Pathway:69206] G1/S Transition - v60:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9790688] Update Tracker - [Pathway:69206] G1/S Transition - v33:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9789487] Update Tracker - [Pathway:69206] G1/S Transition - v38:[updateContainedPathway] [UpdateTracker:9779797] Update Tracker - [Pathway:69206] G1/S Transition - v64:[updateContainedPathway] [UpdateTracker:9783543] Update Tracker - [Pathway:69206] G1/S Transition - v56:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9788820] Update Tracker - [Pathway:69206] G1/S Transition - v40:[modifyText, updateContainedPathway, updateIndirectRLE] [UpdateTracker:9782964] Update Tracker - [Pathway:69206] G1/S Transition - v58:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9776968] Update Tracker - [Pathway:69206] G1/S Transition - v73:[updateIndirectRLE]

Referrals

(updatedInstance)	[UpdateTracker:9779261] Update Tracker - [Pathway:69206] G1/S Transition - v66:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9779360] Update Tracker - [Pathway:69206] G1/S Transition - v65:[updateIndirectRLE] [UpdateTracker:9792201] Update Tracker - [Pathway:69206] G1/S Transition - v22:[updateIndirectRLE] [UpdateTracker:9786724] Update Tracker - [Pathway:69206] G1/S Transition - v48:[updateContainedPathway] [UpdateTracker:9775445] Update Tracker - [Pathway:69206] G1/S Transition - v79:[updateIndirectRLE] [UpdateTracker:9778368] Update Tracker - [Pathway:69206] G1/S Transition - v68:[updateContainedPathway] [UpdateTracker:9780352] Update Tracker - [Pathway:69206] G1/S Transition - v63:[updateContainedPathway] [UpdateTracker:9787171] Update Tracker - [Pathway:69206] G1/S Transition - v46:[updateIndirectRLE] [UpdateTracker:9775703] Update Tracker - [Pathway:69206] G1/S Transition - v78:[updateIndirectRLE] [UpdateTracker:9791954] Update Tracker - [Pathway:69206] G1/S Transition - v24:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9781551] Update Tracker - [Pathway:69206] G1/S Transition - v60:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9790688] Update Tracker - [Pathway:69206] G1/S Transition - v33:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9789487] Update Tracker - [Pathway:69206] G1/S Transition - v38:[updateContainedPathway] [UpdateTracker:9779797] Update Tracker - [Pathway:69206] G1/S Transition - v64:[updateContainedPathway] [UpdateTracker:9783543] Update Tracker - [Pathway:69206] G1/S Transition - v56:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9788820] Update Tracker - [Pathway:69206] G1/S Transition - v40:[modifyText, updateContainedPathway, updateIndirectRLE] [UpdateTracker:9782964] Update Tracker - [Pathway:69206] G1/S Transition - v58:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9776968] Update Tracker - [Pathway:69206] G1/S Transition - v73:[updateIndirectRLE]
(precedingEvent)	[Pathway:R-HSA-69242] S Phase [Pathway:R-HSA-69190] DNA strand elongation
(hasEvent)	[Pathway:R-HSA-453279] Mitotic G1 phase and G1/S transition

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