Reactome | RFC dissociates after sliding clamp formation

Schema > Reaction > Entries

RFC dissociates after sliding clamp formation Show undefined attributes

category	dissociation
compartment	[Compartment:7660] nucleoplasm
dbId	69068
displayName	RFC dissociates after sliding clamp formation
eventOf	[Pathway:R-HSA-69091] Polymerase switching - Homo sapiens
followingEvent	[Reaction:R-HSA-69074] Formation of Processive Complex - Homo sapiens
input	[Complex:R-HSA-68471] RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:69070] Replication factor C disengages from proliferating cell nuclear antigen (PCNA) upon sliding clamp formation, and PCNA itself tethers DNA polymerase delta to DNA.
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	RFC dissociates after sliding clamp formation
orthologousEvent	[Reaction:R-PFA-69068] RFC dissociates after sliding clamp formation - Plasmodium falciparum [Reaction:R-SCE-69068] RFC dissociates after sliding clamp formation - Saccharomyces cerevisiae [Reaction:R-SPO-69068] RFC dissociates after sliding clamp formation - Schizosaccharomyces pombe [Reaction:R-DDI-69068] RFC dissociates after sliding clamp formation - Dictyostelium discoideum [Reaction:R-CEL-69068] RFC dissociates after sliding clamp formation - Caenorhabditis elegans [Reaction:R-DME-69068] RFC dissociates after sliding clamp formation - Drosophila melanogaster [Reaction:R-GGA-69068] RFC dissociates after sliding clamp formation - Gallus gallus [Reaction:R-DRE-69068] RFC dissociates after sliding clamp formation - Danio rerio [Reaction:R-SSC-69068] RFC dissociates after sliding clamp formation - Sus scrofa [Reaction:R-BTA-69068] RFC dissociates after sliding clamp formation - Bos taurus [Reaction:R-CFA-69068] RFC dissociates after sliding clamp formation - Canis familiaris [Reaction:R-RNO-69068] RFC dissociates after sliding clamp formation - Rattus norvegicus [Reaction:R-MMU-69068] RFC dissociates after sliding clamp formation - Mus musculus
output	[Complex:R-HSA-68436] RFC Heteropentamer [nucleoplasm] [Complex:R-HSA-68441] RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm]
precedingEvent	[Reaction:R-HSA-69063] Loading of PCNA - Sliding Clamp Formation - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-69068
summation	[Summation:69069] It is assumed that, as shown for generic DNA replication (Po...
updateTrackers	[UpdateTracker:9792304] Update Tracker - [Reaction:69068] RFC dissociates after sliding clamp formation - v22:[addLiteratureReference] [UpdateTracker:9777111] Update Tracker - [Reaction:69068] RFC dissociates after sliding clamp formation - v72:[modifyText] [UpdateTracker:9776935] Update Tracker - [Reaction:69068] RFC dissociates after sliding clamp formation - v73:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9792304] Update Tracker - [Reaction:69068] RFC dissociates after sliding clamp formation - v22:[addLiteratureReference] [UpdateTracker:9777111] Update Tracker - [Reaction:69068] RFC dissociates after sliding clamp formation - v72:[modifyText] [UpdateTracker:9776935] Update Tracker - [Reaction:69068] RFC dissociates after sliding clamp formation - v73:[modifyText]
(hasEvent)	[Pathway:R-HSA-69091] Polymerase switching
(precedingEvent)	[Reaction:R-HSA-69074] Formation of Processive Complex

Cite Us!