Reactome | NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT

Schema > Reaction > Entries

NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT Show undefined attributes

authored	[InstanceEdit:6810477] Jassal, Bijay, 2015-11-17
catalystActivity	[CatalystActivity:6810534] coenzyme A diphosphatase activity of NUDT19 [peroxisomal matrix]
category	transition
compartment	[Compartment:17951] peroxisomal matrix
created	[InstanceEdit:6810477] Jassal, Bijay, 2015-11-17
crossReference	[DatabaseIdentifier:12667734] RHEA:50045 [DatabaseIdentifier:9914127] RHEA:50045
dbId	6810474
displayName	NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT
edited	[InstanceEdit:6810477] Jassal, Bijay, 2015-11-17
eventOf	[Pathway:R-HSA-390918] Peroxisomal lipid metabolism - Homo sapiens
input	[SimpleEntity:R-ALL-6810523] acyl-CoA [peroxisomal matrix] [SimpleEntity:R-ALL-141343] H2O [peroxisomal matrix]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6810526] Proteomic analysis of mouse kidney peroxisomes: identification of RP2p as a peroxisomal nudix hydrolase with acyl-CoA diphosphatase activity
maxDepth	1
modified	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name	NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT an acyl-CoA + H2O => adenosine 3',5'-bisphosphate + an acyl-4'-phosphopantetheine + 2 H(+)
orthologousEvent	[Reaction:R-DDI-6810474] NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT - Dictyostelium discoideum [Reaction:R-CEL-6810474] NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT - Caenorhabditis elegans [Reaction:R-DME-6810474] NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT - Drosophila melanogaster [Reaction:R-GGA-6810474] NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT - Gallus gallus [Reaction:R-XTR-6810474] NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT - Xenopus tropicalis [Reaction:R-DRE-6810474] NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT - Danio rerio [Reaction:R-SSC-6810474] NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT - Sus scrofa [Reaction:R-BTA-6810474] NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT - Bos taurus [Reaction:R-CFA-6810474] NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT - Canis familiaris [Reaction:R-RNO-6810474] NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT - Rattus norvegicus [Reaction:R-MMU-6810474] NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT - Mus musculus
output	[SimpleEntity:R-ALL-6810530] acyl-PPANT [peroxisomal matrix] 2 × [SimpleEntity:R-ALL-193465] H+ [peroxisomal matrix] [SimpleEntity:R-ALL-9641154] PAP [peroxisomal matrix]
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8851787] D'Eustachio, Peter, 2016-01-11 [InstanceEdit:9917333] Hill, David P, 2024-08-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6810474
summation	[Summation:6810533] Coenzyme A (CoA-SH) and acyl-coenzyme A (acyl-CoA) can be de...
updateTrackers	[UpdateTracker:9919480] Update Tracker - [Reaction:6810474] NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT - v90:[add_removeOutput] [UpdateTracker:9783257] Update Tracker - [Reaction:6810474] NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT - v57:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9919480] Update Tracker - [Reaction:6810474] NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT - v90:[add_removeOutput] [UpdateTracker:9783257] Update Tracker - [Reaction:6810474] NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT - v57:[modifyText]
(hasEvent)	[Pathway:R-HSA-390918] Peroxisomal lipid metabolism