Reactome | MTMR2:SBF1 [endoplasmic reticulum membrane]

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MTMR2:SBF1 [endoplasmic reticulum membrane] Show undefined attributes

catalystActivities	[CatalystActivity:6809771] phosphatidylinositol-3-phosphate phosphatase activity of MTMR2:SBF1 [endoplasmic reticulum membrane] [CatalystActivity:6809772] phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity of MTMR2:SBF1 [endoplasmic reticulum membrane]
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:6809751] Orlic-Milacic, Marija, 2015-11-12
dbId	6809761
displayName	MTMR2:SBF1 [endoplasmic reticulum membrane]
hasComponent	[EntityWithAccessionedSequence:R-HSA-1604662] MTMR2 [cytosol] [EntityWithAccessionedSequence:R-HSA-6809747] SBF1 [endoplasmic reticulum membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-6809761] MTMR2:SBF1 [endoplasmic reticulum membrane] - Mus musculus [Complex:R-RNO-6809761] MTMR2:SBF1 [endoplasmic reticulum membrane] - Rattus norvegicus [Complex:R-CFA-6809761] MTMR2:SBF1 [endoplasmic reticulum membrane] - Canis familiaris [Complex:R-BTA-6809761] MTMR2:SBF1 [endoplasmic reticulum membrane] - Bos taurus [Complex:R-SSC-6809761] MTMR2:SBF1 [endoplasmic reticulum membrane] - Sus scrofa [Complex:R-DRE-6809761] MTMR2:SBF1 [endoplasmic reticulum membrane] - Danio rerio [Complex:R-GGA-6809761] MTMR2:SBF1 [endoplasmic reticulum membrane] - Gallus gallus [Complex:R-DME-6809761] MTMR2:SBF1 [endoplasmic reticulum membrane] - Drosophila melanogaster [Complex:R-CEL-6809761] MTMR2:SBF1 [endoplasmic reticulum membrane] - Caenorhabditis elegans [Complex:R-DDI-6809761] MTMR2:SBF1 [endoplasmic reticulum membrane] - Dictyostelium discoideum [Complex:R-SPO-6809761] MTMR2:SBF1 [endoplasmic reticulum membrane] - Schizosaccharomyces pombe [Complex:R-SCE-6809761] MTMR2:SBF1 [endoplasmic reticulum membrane] - Saccharomyces cerevisiae
isChimeric	false
literatureReference	[LiteratureReference:6809750] Regulation of myotubularin-related (MTMR)2 phosphatidylinositol phosphatase by MTMR5, a catalytically inactive phosphatase [LiteratureReference:6809759] SBF-1 exerts strong anticervical cancer effect through inducing endoplasmic reticulum stress-associated cell death via targeting sarco/endoplasmic reticulum Ca(2+)-ATPase 2 [LiteratureReference:6809762] Membrane association of myotubularin-related protein 2 is mediated by a pleckstrin homology-GRAM domain and a coiled-coil dimerization module
maxDepth	2
modified	[InstanceEdit:8879177] Wu, G, 2016-07-15
name	MTMR2:SBF1 MTMR2:MTMR5
producedByEvent	[Reaction:R-HSA-6809764] SBF1 binds MTMR2 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-6809761

Referrals

(physicalEntity)	[CatalystActivity:6809771] phosphatidylinositol-3-phosphate phosphatase activity of MTMR2:SBF1 [endoplasmic reticulum membrane] [CatalystActivity:6809772] phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity of MTMR2:SBF1 [endoplasmic reticulum membrane]
(output)	[Reaction:R-HSA-6809764] SBF1 binds MTMR2

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