Reactome | ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG

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ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG Show undefined attributes

authored	[InstanceEdit:6808508] D'Eustachio, Peter, 2015-11-04
catalystActivity	[CatalystActivity:6808492] aldehyde dehydrogenase (NAD+) activity of ADH1L2 tetramer [mitochondrial matrix]
catalystActivityReference	[CatalystActivityReference:9643060] aldehyde dehydrogenase (NAD) activity of ADH1L2 tetramer [mitochondrial matrix] ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:6808500] D'Eustachio, Peter, 2015-11-04
dbId	6808487
displayName	ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG
edited	[InstanceEdit:6808508] D'Eustachio, Peter, 2015-11-04
eventOf	[Pathway:R-HSA-196757] Metabolism of folate and pterines - Homo sapiens
input	[SimpleEntity:R-ALL-6808499] 10-formyl-THFPG [mitochondrial matrix] [SimpleEntity:R-ALL-113521] H2O [mitochondrial matrix] [SimpleEntity:R-ALL-113563] NADP+ [mitochondrial matrix]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6808497] ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase [LiteratureReference:6808494] Enzymatic properties of ALDH1L2, a mitochondrial 10-formyltetrahydrofolate dehydrogenase
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG
orthologousEvent	[Reaction:R-CEL-6808487] ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG - Caenorhabditis elegans [Reaction:R-DME-6808487] ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG - Drosophila melanogaster [Reaction:R-GGA-6808487] ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG - Gallus gallus [Reaction:R-XTR-6808487] ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG - Xenopus tropicalis [Reaction:R-SSC-6808487] ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG - Sus scrofa [Reaction:R-BTA-6808487] ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG - Bos taurus [Reaction:R-CFA-6808487] ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG - Canis familiaris [Reaction:R-RNO-6808487] ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG - Rattus norvegicus [Reaction:R-MMU-6808487] ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG - Mus musculus
output	[SimpleEntity:R-ALL-29376] CO2 [mitochondrial matrix] [SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix] [SimpleEntity:R-ALL-113600] NADPH [mitochondrial matrix] [SimpleEntity:R-ALL-200679] THFPG [mitochondrial matrix]
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8847416] Jassal, Bijay, 2015-11-30
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6808487
summation	[Summation:6808488] ALDH1L2 (mitochondrial 10-formyltetrahydrofolate dehydrogena...

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[Pathway:R-HSA-196757] Metabolism of folate and pterines