Reactome | CK2 binds FACT

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CK2 binds FACT Show undefined attributes

authored	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:6805049] Orlic-Milacic, Marija, 2015-10-16
dbId	6805061
displayName	CK2 binds FACT
edited	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
eventOf	[Pathway:R-HSA-6804756] Regulation of TP53 Activity through Phosphorylation - Homo sapiens
followingEvent	[Reaction:R-HSA-6805059] CK2:FACT phosphorylates TP53 - Homo sapiens
input	[Complex:R-HSA-6805066] Casein kinase II [nucleoplasm] [Complex:R-HSA-112417] FACT complex [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6805050] p53 serine 392 phosphorylation increases after UV through induction of the assembly of the CK2.hSPT16.SSRP1 complex [LiteratureReference:6805051] A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	CK2 binds FACT
orthologousEvent	[Reaction:R-PFA-6805061] CK2 binds FACT - Plasmodium falciparum [Reaction:R-SCE-6805061] CK2 binds FACT - Saccharomyces cerevisiae [Reaction:R-SPO-6805061] CK2 binds FACT - Schizosaccharomyces pombe [Reaction:R-DDI-6805061] CK2 binds FACT - Dictyostelium discoideum [Reaction:R-CEL-6805061] CK2 binds FACT - Caenorhabditis elegans [Reaction:R-DME-6805061] CK2 binds FACT - Drosophila melanogaster [Reaction:R-DRE-6805061] CK2 binds FACT - Danio rerio [Reaction:R-SSC-6805061] CK2 binds FACT - Sus scrofa [Reaction:R-BTA-6805061] CK2 binds FACT - Bos taurus [Reaction:R-CFA-6805061] CK2 binds FACT - Canis familiaris [Reaction:R-RNO-6805061] CK2 binds FACT - Rattus norvegicus [Reaction:R-MMU-6805061] CK2 binds FACT - Mus musculus
output	[Complex:R-HSA-6805062] CK2:FACT [nucleoplasm]
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8855677] Zaccara, Sara, 2016-02-04 [InstanceEdit:8855680] Inga, Alberto, 2016-02-04
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6805061
summation	[Summation:6805048] In response to UV radiation, the casein kinase II (CK2) comp...

Referrals

(hasEvent)	[Pathway:R-HSA-6804756] Regulation of TP53 Activity through Phosphorylation
(precedingEvent)	[Reaction:R-HSA-6805059] CK2:FACT phosphorylates TP53