Reactome | KDM7A(1-476)-p-BRAF(439-766) fusion [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-6802691] p-KDM7A-BRAF fusion dimer [cytosol] - Homo sapiens [Complex:R-HSA-6802691] p-KDM7A-BRAF fusion dimer [cytosol] - Homo sapiens
created	[InstanceEdit:6802532] Rothfels, Karen, 2015-10-02
crossReference	[DatabaseIdentifier:12021112] Mondo:0005082
dbId	6802531
disease	[Disease:1655494] prostate adenocarcinoma [Disease:1500689] cancer
displayName	KDM7A(1-476)-p-BRAF(439-766) fusion [cytosol]
endCoordinate	476
hasModifiedResidue	[FragmentInsertionModification:6802390] Insertion of residues 439 to 766 at 477 from UniProt:P15056 BRAF [ModifiedResidue:5672668] O-phospho-L-serine at 446 [ModifiedResidue:5672670] O-phospho-L-serine at 729 [ModifiedResidue:5672675] O-phospho-L-threonine at 599 [ModifiedResidue:5672677] O-phospho-L-serine at 602
inDisease	true
literatureReference	[LiteratureReference:6800639] The landscape of kinase fusions in cancer
maxDepth	1
modified	[InstanceEdit:9753817] Rothfels, Karen, 2021-09-13
name	KDM7A(1-476)-p-BRAF(439-766) fusion
referenceEntity	[ReferenceGeneProduct:uniprot:Q6ZMT4] UniProt:Q6ZMT4 KDM7A
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-6802531
startCoordinate	1
updateTrackers	[UpdateTracker:9902841] Update Tracker - [EntityWithAccessionedSequence:6802531] KDM7A(1-476)-p-BRAF(439-766) fusion [cytosol] - v79:[modifyName]

(updatedInstance)	[UpdateTracker:9902841] Update Tracker - [EntityWithAccessionedSequence:6802531] KDM7A(1-476)-p-BRAF(439-766) fusion [cytosol] - v79:[modifyName]
(hasComponent)	[Complex:R-HSA-6802691] p-KDM7A-BRAF fusion dimer [cytosol]

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