Reactome | BCL2L11(1-131)-p-BRAF(397-766) fusion [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-6802688] p-BCL2L11-BRAF fusion dimer [cytosol] - Homo sapiens [Complex:R-HSA-6802688] p-BCL2L11-BRAF fusion dimer [cytosol] - Homo sapiens
created	[InstanceEdit:6802520] Rothfels, Karen, 2015-10-02
crossReference	[DatabaseIdentifier:12021093] Mondo:0015075
dbId	6802519
disease	[Disease:1500689] cancer [Disease:6802256] thyroid carcinoma
displayName	BCL2L11(1-131)-p-BRAF(397-766) fusion [cytosol]
endCoordinate	131
hasModifiedResidue	[FragmentInsertionModification:6802278] Insertion of residues 397 to 766 at 132 from UniProt:P15056 BRAF [ModifiedResidue:5672668] O-phospho-L-serine at 446 [ModifiedResidue:5672670] O-phospho-L-serine at 729 [ModifiedResidue:5672675] O-phospho-L-threonine at 599 [ModifiedResidue:5672677] O-phospho-L-serine at 602
inDisease	true
literatureReference	[LiteratureReference:6800639] The landscape of kinase fusions in cancer
maxDepth	1
modified	[InstanceEdit:9753817] Rothfels, Karen, 2021-09-13
name	BCL2L11(1-131)-p-BRAF(397-766) fusion
referenceEntity	[ReferenceGeneProduct:uniprot:O43521] UniProt:O43521 BCL2L11
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-6802519
startCoordinate	1
updateTrackers	[UpdateTracker:9902943] Update Tracker - [EntityWithAccessionedSequence:6802519] BCL2L11(1-131)-p-BRAF(397-766) fusion [cytosol] - v79:[modifyName]

(updatedInstance)	[UpdateTracker:9902943] Update Tracker - [EntityWithAccessionedSequence:6802519] BCL2L11(1-131)-p-BRAF(397-766) fusion [cytosol] - v79:[modifyName]
(hasComponent)	[Complex:R-HSA-6802688] p-BCL2L11-BRAF fusion dimer [cytosol]

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