Reactome | LMNA(1-567)-RAF1(279-648) fusion [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-6802595] LMNA-RAF1 fusion dimer [cytosol] - Homo sapiens [Complex:R-HSA-6802595] LMNA-RAF1 fusion dimer [cytosol] - Homo sapiens
created	[InstanceEdit:6802400] Rothfels, Karen, 2015-10-02
crossReference	[DatabaseIdentifier:12021100] Mondo:0005012
dbId	6802399
disease	[Disease:1500689] cancer [Disease:6802273] skin melanoma
displayName	LMNA(1-567)-RAF1(279-648) fusion [cytosol]
endCoordinate	567
hasModifiedResidue	[FragmentInsertionModification:6802401] Insertion of residues 279 to 648 at 568 from UniProt:P04049 RAF1 [ModifiedResidue:109785] O-phospho-L-serine at 621
inDisease	true
literatureReference	[LiteratureReference:6800639] The landscape of kinase fusions in cancer
maxDepth	1
modified	[InstanceEdit:9753816] Rothfels, Karen, 2021-09-13
name	LMNA(1-567)-RAF1(279-648) fusion
referenceEntity	[ReferenceGeneProduct:uniprot:P02545] UniProt:P02545 LMNA
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-6802399
startCoordinate	1
updateTrackers	[UpdateTracker:9902816] Update Tracker - [EntityWithAccessionedSequence:6802399] LMNA(1-567)-RAF1(279-648) fusion [cytosol] - v79:[modifyName]

(updatedInstance)	[UpdateTracker:9902816] Update Tracker - [EntityWithAccessionedSequence:6802399] LMNA(1-567)-RAF1(279-648) fusion [cytosol] - v79:[modifyName]
(hasComponent)	[Complex:R-HSA-6802595] LMNA-RAF1 fusion dimer [cytosol]

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