Reactome | AKAP9(1-1118)-BRAF(381-766) fusion [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-6802570] AKAP9-BRAF fusion dimer [cytosol] - Homo sapiens [Complex:R-HSA-6802570] AKAP9-BRAF fusion dimer [cytosol] - Homo sapiens
created	[InstanceEdit:6802266] Rothfels, Karen, 2015-10-02
crossReference	[DatabaseIdentifier:12021030] Mondo:0002108
dbId	6802267
disease	[Disease:1500689] cancer [Disease:1655470] thyroid cancer
displayName	AKAP9(1-1118)-BRAF(381-766) fusion [cytosol]
endCoordinate	1118
hasModifiedResidue	[FragmentInsertionModification:6802268] Insertion of residues 381 to 766 at 1119 from UniProt:P15056 BRAF [ModifiedResidue:5672668] O-phospho-L-serine at 446 [ModifiedResidue:5672670] O-phospho-L-serine at 729
inDisease	true
literatureReference	[LiteratureReference:6802072] Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer
maxDepth	1
modified	[InstanceEdit:9753816] Rothfels, Karen, 2021-09-13
name	AKAP9(1-1118)-BRAF(381-766) fusion
referenceEntity	[ReferenceGeneProduct:uniprot:Q99996] UniProt:Q99996 AKAP9
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-6802267
startCoordinate	1
updateTrackers	[UpdateTracker:9902878] Update Tracker - [EntityWithAccessionedSequence:6802267] AKAP9(1-1118)-BRAF(381-766) fusion [cytosol] - v79:[modifyName]

(updatedInstance)	[UpdateTracker:9902878] Update Tracker - [EntityWithAccessionedSequence:6802267] AKAP9(1-1118)-BRAF(381-766) fusion [cytosol] - v79:[modifyName]
(hasComponent)	[Complex:R-HSA-6802570] AKAP9-BRAF fusion dimer [cytosol]

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