Reactome | REG3A binds bacterial phospholipids

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REG3A binds bacterial phospholipids Show undefined attributes

authored	[InstanceEdit:6803156] Shamovsky, Veronica, 2015-10-05
category	binding
compartment	[Compartment:984] extracellular region [Compartment:25409] peptidoglycan-based cell wall
created	[InstanceEdit:6801765] Shamovsky, Veronica, 2015-10-02
dbId	6801776
displayName	REG3A binds bacterial phospholipids
edited	[InstanceEdit:8935852] Shamovsky, Veronica, 2016-08-15
entityOnOtherCell	[Complex:R-ALL-8931784] Anionic phospholipids:microbial cell surface [plasma membrane]
eventOf	[Pathway:R-HSA-6803157] Antimicrobial peptides - Homo sapiens
followingEvent	[Reaction:R-HSA-6801762] REG3A oligomerize to form a pore complex - Homo sapiens
input	[Complex:R-ALL-8931784] Anionic phospholipids:microbial cell surface [plasma membrane] [EntityWithAccessionedSequence:R-HSA-6801352] REG3A(38-175) [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6801775] Antibacterial membrane attack by a pore-forming intestinal C-type lectin
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	REG3A binds bacterial phospholipids
orthologousEvent	[Reaction:R-MMU-6801776] REG3A binds bacterial phospholipids - Mus musculus [Reaction:R-CEL-6801776] REG3A binds bacterial phospholipids - Caenorhabditis elegans [Reaction:R-DME-6801776] REG3A binds bacterial phospholipids - Drosophila melanogaster [Reaction:R-GGA-6801776] REG3A binds bacterial phospholipids - Gallus gallus [Reaction:R-XTR-6801776] REG3A binds bacterial phospholipids - Xenopus tropicalis [Reaction:R-SSC-6801776] REG3A binds bacterial phospholipids - Sus scrofa [Reaction:R-BTA-6801776] REG3A binds bacterial phospholipids - Bos taurus [Reaction:R-CFA-6801776] REG3A binds bacterial phospholipids - Canis familiaris [Reaction:R-RNO-6801776] REG3A binds bacterial phospholipids - Rattus norvegicus
output	[Complex:R-HSA-6801804] REG3A(38-175):anionic phospholipids [extracellular region]
precedingEvent	[BlackBoxEvent:R-HSA-6801766] Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175) - Homo sapiens
releaseDate	2016-09-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8933035] Hains, David S, 2016-08-02 [InstanceEdit:8867536] Jupe, Steve, 2016-04-15
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6801776
summation	[Summation:6801790] Structural studies of human REG3A by X-ray diffraction with ...

Referrals

(hasEvent)	[Pathway:R-HSA-6803157] Antimicrobial peptides
(precedingEvent)	[Reaction:R-HSA-6801762] REG3A oligomerize to form a pore complex