Reactome | RABGGTA binds RABGGTB

Schema > Reaction > Entries

RABGGTA binds RABGGTB Show undefined attributes

authored	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:6801103] Orlic-Milacic, Marija, 2015-09-30
dbId	6801101
displayName	RABGGTA binds RABGGTB
edited	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
eventOf	[Pathway:R-HSA-6803205] TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain - Homo sapiens
followingEvent	[Reaction:R-HSA-6801109] CHM binds RGGT - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-6801086] RABGGTA [plasma membrane] [EntityWithAccessionedSequence:R-HSA-6801098] RABGGTB [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6801102] Rab geranylgeranylation occurs preferentially via the pre-formed REP-RGGT complex and is regulated by geranylgeranyl pyrophosphate [LiteratureReference:6801100] Rab geranylgeranyl transferase. A multisubunit enzyme that prenylates GTP-binding proteins terminating in Cys-X-Cys or Cys-Cys
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	RABGGTA binds RABGGTB
orthologousEvent	[Reaction:R-PFA-6801101] RABGGTA binds RABGGTB - Plasmodium falciparum [Reaction:R-SCE-6801101] RABGGTA binds RABGGTB - Saccharomyces cerevisiae [Reaction:R-SPO-6801101] RABGGTA binds RABGGTB - Schizosaccharomyces pombe [Reaction:R-DDI-6801101] RABGGTA binds RABGGTB - Dictyostelium discoideum [Reaction:R-CEL-6801101] RABGGTA binds RABGGTB - Caenorhabditis elegans [Reaction:R-DME-6801101] RABGGTA binds RABGGTB - Drosophila melanogaster [Reaction:R-DRE-6801101] RABGGTA binds RABGGTB - Danio rerio [Reaction:R-BTA-6801101] RABGGTA binds RABGGTB - Bos taurus [Reaction:R-CFA-6801101] RABGGTA binds RABGGTB - Canis familiaris [Reaction:R-RNO-6801101] RABGGTA binds RABGGTB - Rattus norvegicus [Reaction:R-MMU-6801101] RABGGTA binds RABGGTB - Mus musculus
output	[Complex:R-HSA-6801105] RGGT [plasma membrane]
precedingEvent	[BlackBoxEvent:R-HSA-6801089] TP53 stimulates RABGGTA expression - Homo sapiens
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8855677] Zaccara, Sara, 2016-02-04 [InstanceEdit:8855680] Inga, Alberto, 2016-02-04
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6801101
summation	[Summation:6801107] RABGGTA associates with RABGGTB to form RAB geranylgeranyl t...

Referrals

(precedingEvent)	[Reaction:R-HSA-6801109] CHM binds RGGT
(hasEvent)	[Pathway:R-HSA-6803205] TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain