Reactome | MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG

Schema > Reaction > Entries

MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG Show undefined attributes

authored	[InstanceEdit:6800348] Jassal, Bijay, 2015-09-29
catalystActivity	[CatalystActivity:6800350] 2-acylglycerol O-acyltransferase activity of MOGAT1,2,3 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:6800348] Jassal, Bijay, 2015-09-29
crossReference	[DatabaseIdentifier:12668373] RHEA:32948
dbId	6800334
displayName	MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG
edited	[InstanceEdit:6800348] Jassal, Bijay, 2015-09-29
eventOf	[Pathway:R-HSA-75109] Triglyceride biosynthesis - Homo sapiens
input	[SimpleEntity:R-ALL-6800352] 2AG [cytosol] [SimpleEntity:R-ALL-1500578] acyl-CoA [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6800342] Identification of acyl coenzyme A:monoacylglycerol acyltransferase 3, an intestinal specific enzyme implicated in dietary fat absorption [LiteratureReference:6800347] Human intestinal monoacylglycerol acyltransferase: differential features in tissue expression and activity [LiteratureReference:6800335] Genomic organization of the DGAT2/MOGAT gene family in cattle (Bos taurus) and other mammals [LiteratureReference:6800321] Monoacylglycerol O-acyltransferase 1 is regulated by peroxisome proliferator-activated receptor γ in human hepatocytes and increases lipid accumulation
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG
orthologousEvent	[Reaction:R-SCE-6800334] MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG - Saccharomyces cerevisiae [Reaction:R-SPO-6800334] MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG - Schizosaccharomyces pombe [Reaction:R-DDI-6800334] MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG - Dictyostelium discoideum [Reaction:R-CEL-6800334] MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG - Caenorhabditis elegans [Reaction:R-DME-6800334] MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG - Drosophila melanogaster [Reaction:R-GGA-6800334] MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG - Gallus gallus [Reaction:R-XTR-6800334] MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG - Xenopus tropicalis [Reaction:R-DRE-6800334] MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG - Danio rerio [Reaction:R-SSC-6800334] MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG - Sus scrofa [Reaction:R-BTA-6800334] MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG - Bos taurus [Reaction:R-CFA-6800334] MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG - Canis familiaris [Reaction:R-RNO-6800334] MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG - Rattus norvegicus [Reaction:R-MMU-6800334] MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG - Mus musculus
output	[SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [SimpleEntity:R-ALL-76103] DAG [cytosol]
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8851787] D'Eustachio, Peter, 2016-01-11
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6800334
summation	[Summation:6800327] Triacylglycerol (TG) is a non-polar acyl triester of glycero...

Referrals

(hasEvent)

[Pathway:R-HSA-75109] Triglyceride biosynthesis

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