Reactome | DLAT [mitochondrial matrix]

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DLAT [mitochondrial matrix] Show undefined attributes

compartment	[Compartment:5460] mitochondrial matrix
consumedByEvent	[Reaction:R-HSA-9858752] LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT - Homo sapiens
created	[InstanceEdit:6792577] Jassal, Bijay, 2015-08-25
dbId	6792585
displayName	DLAT [mitochondrial matrix]
endCoordinate	647
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-6792585] DLAT [mitochondrial matrix] - Mus musculus [EntityWithAccessionedSequence:R-RNO-6792585] DLAT [mitochondrial matrix] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-6792585] DLAT [mitochondrial matrix] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-6792585] DLAT [mitochondrial matrix] - Bos taurus [EntityWithAccessionedSequence:R-SSC-6792585] DLAT [mitochondrial matrix] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-6792585] dlat [mitochondrial matrix] - Danio rerio [EntityWithAccessionedSequence:R-XTR-6792585] dlat [mitochondrial matrix] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-6792585] DLAT [mitochondrial matrix] - Gallus gallus [EntityWithAccessionedSequence:R-DME-6792585] Dlat [mitochondrial matrix] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-6792585] dlat-2 [mitochondrial matrix] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-6792585] pdhC [mitochondrial matrix] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SPO-6792585] lat1 [mitochondrial matrix] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SCE-6792585] LAT1 [mitochondrial matrix] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-PFA-6792585] DLAT [mitochondrial matrix] - Plasmodium falciparum
maxDepth	1
name	DLAT pyruvate dehydrogenase E2 subunit Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex ODP2_HUMAN Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor E2 PDC-E2 70 kDa mitochondrial autoantigen of primary biliary cirrhosis PBC M2 antigen complex 70 kDa subunit
negativelyRegulates	[NegativeRegulation:9861545] Negative regulation by 'DLAT [mitochondrial matrix]'
producedByEvent	[Reaction:R-HSA-9861626] SIRT4 cleaves lipoyl from DLAT - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P10515] UniProt:P10515 DLAT
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-6792585
startCoordinate	87

Referrals

(input)	[Reaction:R-HSA-9858752] LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT
(output)	[Reaction:R-HSA-9861626] SIRT4 cleaves lipoyl from DLAT
(regulator)	[NegativeRegulation:9861545] Negative regulation by 'DLAT [mitochondrial matrix]'

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