Reactome | HVEM induses BTLA phosphorylation

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:388810] Garapati, P V, 2008-12-16 11:12:19
catalystActivity	[CatalystActivity:6790063] protein tyrosine kinase activity of unknown kinase [cytosol]
category	omitted
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:6790086] Garapati, Phani Vijay, 2015-08-07
dbId	6790087
displayName	HVEM induses BTLA phosphorylation
edited	[InstanceEdit:388810] Garapati, P V, 2008-12-16 11:12:19
eventOf	[Pathway:R-HSA-9927353] Co-inhibition by BTLA - Homo sapiens
followingEvent	[Reaction:R-HSA-389919] Grb2 binds pBTLA - Homo sapiens [Reaction:R-HSA-389941] SHP-1 and SHP-2 bind pBTLA - Homo sapiens
inferredFrom	[BlackBoxEvent:R-MMU-6790089] Hvem induses Btla phosphorylation - Mus musculus
input	3 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-HSA-389525] BTLA-HVEM complex [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	HVEM induses BTLA phosphorylation
output	3 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-HSA-389920] p-BTLA-HVEM complex [plasma membrane]
precedingEvent	[Reaction:R-HSA-389523] BTLA interacts with HVEM - Homo sapiens
releaseDate	2015-09-22
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:422514] Bluestone, JA, Esensten, J, 2009-06-01 18:47:33
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-6790087
summation	[Summation:6790088] Binding of HVEM to BTLA induces tyrosine phosphorylation of ...

(precedingEvent)	[Reaction:R-HSA-389919] Grb2 binds pBTLA [Reaction:R-HSA-389941] SHP-1 and SHP-2 bind pBTLA
(hasEvent)	[Pathway:R-HSA-9927353] Co-inhibition by BTLA
(inferredTo)	[BlackBoxEvent:R-MMU-6790089] Hvem induses Btla phosphorylation

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