Reactome | tRNA processing in the mitochondrion

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tRNA processing in the mitochondrion Show undefined attributes

authored	[InstanceEdit:6785467] May, Bruce, 2015-06-28
created	[InstanceEdit:6785469] May, Bruce, 2015-06-28
crossReference	[DatabaseIdentifier:12819585] BioModels Database:BIOMD0000000602
dbId	6785470
displayName	tRNA processing in the mitochondrion
doi	10.3180/R-HSA-6785470.1
edited	[InstanceEdit:6785467] May, Bruce, 2015-06-28
eventOf	[Pathway:R-HSA-72306] tRNA processing - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:6788631] mitochondrial tRNA processing
hasDiagram	true
hasEHLD	false
hasEvent	[BlackBoxEvent:R-HSA-6785722] Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the H strand transcript - Homo sapiens [BlackBoxEvent:R-HSA-6786854] Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the L strand transcript - Homo sapiens [Reaction:R-HSA-6786881] TRNT1 polymerizes CCA at the 3' end of pre-tRNA - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2020-06-17
literatureReference	[LiteratureReference:6784542] Human mitochondrial tRNAs: biogenesis, function, structural aspects, and diseases [LiteratureReference:6786808] Nuclear-encoded factors involved in post-transcriptional processing and modification of mitochondrial tRNAs in human disease [LiteratureReference:6786876] Of P and Z: mitochondrial tRNA processing enzymes [LiteratureReference:6786871] Mitochondrial tRNA import and its consequences for mitochondrial translation [LiteratureReference:6787374] The human mitochondrial transcriptome [LiteratureReference:6787401] tRNA biology in mitochondria [LiteratureReference:6792957] Mitochondrial transcript maturation and its disorders [LiteratureReference:6792647] Modify or die?--RNA modification defects in metazoans
maxDepth	2
modified	[InstanceEdit:12819426] Weiser, Joel, 2026-02-23
name	tRNA processing in the mitochondrion
releaseDate	2015-12-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6790491] Levinger, Louis, 2015-08-10 [InstanceEdit:6792690] Motorin, Yuri, 2015-08-25 [InstanceEdit:6806693] Jarrous, Nayef, 2015-10-24 [InstanceEdit:6808651] Powell, Christopher A, 2015-11-07 [InstanceEdit:6810571] Suzuki, Tsutomu, 2015-11-18
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-6785470
summation	[Summation:6786815] Each strand of the circular mitochondrial genome is transcri...
updateTrackers	[UpdateTracker:9776983] Update Tracker - [Pathway:6785470] tRNA processing in the mitochondrion - v73:[updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9776983] Update Tracker - [Pathway:6785470] tRNA processing in the mitochondrion - v73:[updateContainedRLE]
(hasEvent)	[Pathway:R-HSA-72306] tRNA processing