Reactome | LMF1,2 transport LIPC dimer from ER lumen to extracellular region

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LMF1,2 transport LIPC dimer from ER lumen to extracellular region Show undefined attributes

authored	[InstanceEdit:6785192] Jassal, Bijay, 2015-06-25
category	omitted
compartment	[Compartment:17957] endoplasmic reticulum lumen [Compartment:12045] endoplasmic reticulum membrane [Compartment:984] extracellular region
created	[InstanceEdit:6785192] Jassal, Bijay, 2015-06-25
dbId	6785178
displayName	LMF1,2 transport LIPC dimer from ER lumen to extracellular region
edited	[InstanceEdit:6785192] Jassal, Bijay, 2015-06-25
eventOf	[Pathway:R-HSA-8963889] Assembly of active LPL and LIPC lipase complexes - Homo sapiens
followingEvent	[Reaction:R-HSA-6785213] LIPC dimer binds heparin - Homo sapiens
input	[Complex:R-HSA-6785173] LIPC dimer:LMF1,2 [endoplasmic reticulum membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6785202] Hepatic lipase: high-level expression and subunit structure determination [LiteratureReference:6785184] Purification, cellular levels, and functional domains of lipase maturation factor 1 [LiteratureReference:6785169] Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	LMF1,2 transport LIPC dimer from ER lumen to extracellular region
orthologousEvent	[BlackBoxEvent:R-GGA-6785178] LMF1,2 transport LIPC dimer from ER lumen to extracellular region - Gallus gallus [BlackBoxEvent:R-XTR-6785178] LMF1,2 transport LIPC dimer from ER lumen to extracellular region - Xenopus tropicalis [BlackBoxEvent:R-SSC-6785178] LMF1,2 transport LIPC dimer from ER lumen to extracellular region - Sus scrofa [BlackBoxEvent:R-BTA-6785178] LMF1,2 transport LIPC dimer from ER lumen to extracellular region - Bos taurus [BlackBoxEvent:R-RNO-6785178] LMF1,2 transport LIPC dimer from ER lumen to extracellular region - Rattus norvegicus [BlackBoxEvent:R-MMU-6785178] LMF1,2 transport LIPC dimer from ER lumen to extracellular region - Mus musculus
output	[Complex:R-HSA-6785179] LIPC dimer [extracellular region] [CandidateSet:R-HSA-6785148] LMF1,2 [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-HSA-6785181] LMF1,2 bind LIPC dimer - Homo sapiens
releaseDate	2015-09-22
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6785241] D'Eustachio, Peter, 2015-06-26
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-6785178
summation	[Summation:6785176] Hepatic triacylglycerol lipase (LIPC, and lipoprotein lipase...
updateTrackers	[UpdateTracker:9863978] Update Tracker - [BlackBoxEvent:6785178] LMF1,2 transport LIPC dimer from ER lumen to extracellular region - v88:[modifyText, removeLiteratureReference]

Referrals

(updatedInstance)	[UpdateTracker:9863978] Update Tracker - [BlackBoxEvent:6785178] LMF1,2 transport LIPC dimer from ER lumen to extracellular region - v88:[modifyText, removeLiteratureReference]
(hasEvent)	[Pathway:R-HSA-8963889] Assembly of active LPL and LIPC lipase complexes
(precedingEvent)	[Reaction:R-HSA-6785213] LIPC dimer binds heparin