Reactome | Deposition of new CENPA-containing nucleosomes at the centromere

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Deposition of new CENPA-containing nucleosomes at the centromere Show undefined attributes

authored	[InstanceEdit:599714] May, B, 2010-04-15
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:606312] May, B, 2010-04-17
dbId	606279
displayName	Deposition of new CENPA-containing nucleosomes at the centromere
edited	[InstanceEdit:599714] May, B, 2010-04-15
eventOf	[Pathway:R-HSA-774815] Nucleosome assembly - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:260633] CENP-A containing chromatin assembly
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-606349] Mis18 complex binds the centromere - Homo sapiens [Reaction:R-HSA-606326] HJURP:CENPA complex localizes to the centromere - Homo sapiens [BlackBoxEvent:R-HSA-606289] New CENPA-containing nucleosomes are deposited at the centromere - Homo sapiens [BlackBoxEvent:R-HSA-606287] RSF complex binds the centromere - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2014-12-08
literatureReference	[LiteratureReference:847689] Propagation of centromeric chromatin requires exit from mitosis [LiteratureReference:606283] Centromere-specific assembly of CENP-a nucleosomes is mediated by HJURP [LiteratureReference:606290] HJURP is a cell-cycle-dependent maintenance and deposition factor of CENP-A at centromeres [LiteratureReference:606307] HJURP binds CENP-A via a highly conserved N-terminal domain and mediates its deposition at centromeres [LiteratureReference:606298] Frodos found: Behold the CENP-a "Ring" bearers [LiteratureReference:877404] At the right place at the right time: novel CENP-A binding proteins shed light on centromere assembly [LiteratureReference:877415] Epigenetic specification of centromeres by CENP-A [LiteratureReference:877405] Focus on the centre: the role of chromatin on the regulation of centromere identity and function
maxDepth	2
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Deposition of new CENPA-containing nucleosomes at the centromere
orthologousEvent	[Pathway:R-GGA-606279] Deposition of new CENPA-containing nucleosomes at the centromere - Gallus gallus [Pathway:R-XTR-606279] Deposition of new CENPA-containing nucleosomes at the centromere - Xenopus tropicalis [Pathway:R-SSC-606279] Deposition of new CENPA-containing nucleosomes at the centromere - Sus scrofa [Pathway:R-BTA-606279] Deposition of new CENPA-containing nucleosomes at the centromere - Bos taurus [Pathway:R-CFA-606279] Deposition of new CENPA-containing nucleosomes at the centromere - Canis familiaris [Pathway:R-RNO-606279] Deposition of new CENPA-containing nucleosomes at the centromere - Rattus norvegicus [Pathway:R-MMU-606279] Deposition of new CENPA-containing nucleosomes at the centromere - Mus musculus
releaseDate	2010-06-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:847690] Almouzni-Pettinotti, G, Dunleavy, EM, 2010-05-30 [InstanceEdit:877422] Foltz, DR, 2010-06-14
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-606279
summation	[Summation:606278] Eukaryotic centromeres are marked by a unique form of histon...
updateTrackers	[UpdateTracker:9785815] Update Tracker - [Pathway:606279] Deposition of new CENPA-containing nucleosomes at the centromere - v51:[updateContainedRLE] [UpdateTracker:9790305] Update Tracker - [Pathway:606279] Deposition of new CENPA-containing nucleosomes at the centromere - v34:[addLiteratureReference, modifyText, updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9785815] Update Tracker - [Pathway:606279] Deposition of new CENPA-containing nucleosomes at the centromere - v51:[updateContainedRLE] [UpdateTracker:9790305] Update Tracker - [Pathway:606279] Deposition of new CENPA-containing nucleosomes at the centromere - v34:[addLiteratureReference, modifyText, updateContainedRLE]
(hasEvent)	[Pathway:R-HSA-774815] Nucleosome assembly

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