Reactome | TREM,CD300 binds lipids

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TREM,CD300 binds lipids Show undefined attributes

authored	[InstanceEdit:5696355] Garapati, Phani Vijay, 2015-05-28
category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:5696355] Garapati, Phani Vijay, 2015-05-28
dbId	5696358
displayName	TREM,CD300 binds lipids
edited	[InstanceEdit:5696355] Garapati, Phani Vijay, 2015-05-28
eventOf	[Pathway:R-HSA-198933] Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell - Homo sapiens
input	[DefinedSet:R-ALL-5696348] CERA,PE,PS [plasma membrane] [DefinedSet:R-HSA-5696347] TREM, CD300 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5696326] Specific lipid recognition is a general feature of CD300 and TREM molecules [LiteratureReference:5696258] Gene for familial psoriasis susceptibility mapped to the distal end of human chromosome 17q [LiteratureReference:5696273] Novel immunoglobulin superfamily gene cluster, mapping to a region of human chromosome 17q25, linked to psoriasis susceptibility [LiteratureReference:5696319] The CD300 family of molecules are evolutionarily significant regulators of leukocyte functions [LiteratureReference:5696286] The CD300 molecules regulate monocyte and dendritic cell functions [LiteratureReference:5696330] The CMRF-35H gene structure predicts for an independently expressed member of an ITIM/ITAM pair of molecules localized to human chromosome 17 [LiteratureReference:5696290] The gene encoding the immunoregulatory signaling molecule CMRF-35A localized to human chromosome 17 in close proximity to other members of the CMRF-35 family [LiteratureReference:5696259] Triggering Receptor Expressed on Myeloid Cells (TREM) family and the application of its antagonists
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	TREM,CD300 binds lipids
orthologousEvent	[Reaction:R-GGA-5696358] TREM,CD300 binds lipids - Gallus gallus [Reaction:R-XTR-5696358] TREM,CD300 binds lipids - Xenopus tropicalis [Reaction:R-DRE-5696358] TREM,CD300 binds lipids - Danio rerio [Reaction:R-SSC-5696358] TREM,CD300 binds lipids - Sus scrofa [Reaction:R-BTA-5696358] TREM,CD300 binds lipids - Bos taurus [Reaction:R-CFA-5696358] TREM,CD300 binds lipids - Canis familiaris [Reaction:R-RNO-5696358] TREM,CD300 binds lipids - Rattus norvegicus [Reaction:R-MMU-5696358] TREM,CD300 binds lipids - Mus musculus
output	[Complex:R-HSA-5696352] TRIM, CD300:lipids [plasma membrane]
releaseDate	2015-09-22
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5692843] Barrow, Alexander D, 2015-05-12
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5696358
summation	[Summation:5696236] The CD300 glycoproteins are a family of related leucocyte su...

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(hasEvent)

[Pathway:R-HSA-198933] Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

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