Reactome | MIA2 and MIA3 load procollagen VII into COPII vesicles

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MIA2 and MIA3 load procollagen VII into COPII vesicles Show undefined attributes

authored	[InstanceEdit:5688570] Rothfels, Karen, 2015-04-17
category	binding
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:5694434] Rothfels, Karen, 2015-05-21
dbId	5694435
displayName	MIA2 and MIA3 load procollagen VII into COPII vesicles
edited	[InstanceEdit:5688570] Rothfels, Karen, 2015-04-17
eventOf	[Pathway:R-HSA-5694530] Cargo concentration in the ER - Homo sapiens
input	[Complex:R-HSA-5694290] MIA2:PREB [endoplasmic reticulum membrane] [Complex:R-HSA-5694291] Procollagen type VII:MIA3 [endoplasmic reticulum membrane] [EntityWithAccessionedSequence:R-HSA-203972] SEC23A [cytosol] [EntityWithAccessionedSequence:R-HSA-203988] SEC24C [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5689415] cTAGE5 mediates collagen secretion through interaction with TANGO1 at endoplasmic reticulum exit sites [LiteratureReference:5688541] Procollagen export from the endoplasmic reticulum [LiteratureReference:2127533] Protein export at the ER: loading big collagens into COPII carriers
maxDepth	1
modified	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
name	MIA2 and MIA3 load procollagen VII into COPII vesicles
orthologousEvent	[Reaction:R-DME-5694435] MIA2 and MIA3 load procollagen VII into COPII vesicles - Drosophila melanogaster [Reaction:R-SSC-5694435] MIA2 and MIA3 load procollagen VII into COPII vesicles - Sus scrofa [Reaction:R-RNO-5694435] MIA2 and MIA3 load procollagen VII into COPII vesicles - Rattus norvegicus [Reaction:R-MMU-5694435] MIA2 and MIA3 load procollagen VII into COPII vesicles - Mus musculus
output	[Complex:R-HSA-5694288] procollagen VII:MIA3:MIA2:PREB:SEC23A:SEC24C [endoplasmic reticulum membrane]
releaseDate	2015-09-22
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6791049] Gillespie, Marc E, 2015-08-17
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5694435
summation	[Summation:5694368] MIA2 (also known as CTAGE5) and MIA3 form heterodimers throu...
updateTrackers	[UpdateTracker:9778328] Update Tracker - [Reaction:5694435] MIA2 and MIA3 load procollagen VII into COPII vesicles - v68:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9778328] Update Tracker - [Reaction:5694435] MIA2 and MIA3 load procollagen VII into COPII vesicles - v68:[modifyText]
(hasEvent)	[Pathway:R-HSA-5694530] Cargo concentration in the ER

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