Reactome | SEC4C,D bind GOSR2 and STX5

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SEC4C,D bind GOSR2 and STX5 Show undefined attributes

authored	[InstanceEdit:5688570] Rothfels, Karen, 2015-04-17
category	binding
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:5694412] Rothfels, Karen, 2015-05-21
dbId	5694413
displayName	SEC4C,D bind GOSR2 and STX5
edited	[InstanceEdit:5688570] Rothfels, Karen, 2015-04-17
eventOf	[Pathway:R-HSA-5694530] Cargo concentration in the ER - Homo sapiens
input	[DefinedSet:R-HSA-5694232] GOSR2,STX5 [endoplasmic reticulum membrane] [EntityWithAccessionedSequence:R-HSA-203972] SEC23A [cytosol] [DefinedSet:R-HSA-5694201] SEC24C,D [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5688550] Structural basis of cargo membrane protein discrimination by the human COPII coat machinery
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	SEC4C,D bind GOSR2 and STX5
orthologousEvent	[Reaction:R-BTA-5694413] SEC4C,D bind GOSR2 and STX5 - Bos taurus [Reaction:R-SCE-5694413] SEC4C,D bind GOSR2 and STX5 - Saccharomyces cerevisiae [Reaction:R-SPO-5694413] SEC4C,D bind GOSR2 and STX5 - Schizosaccharomyces pombe [Reaction:R-DDI-5694413] SEC4C,D bind GOSR2 and STX5 - Dictyostelium discoideum [Reaction:R-CEL-5694413] SEC4C,D bind GOSR2 and STX5 - Caenorhabditis elegans [Reaction:R-DME-5694413] SEC4C,D bind GOSR2 and STX5 - Drosophila melanogaster [Reaction:R-GGA-5694413] SEC4C,D bind GOSR2 and STX5 - Gallus gallus [Reaction:R-XTR-5694413] SEC4C,D bind GOSR2 and STX5 - Xenopus tropicalis [Reaction:R-DRE-5694413] SEC4C,D bind GOSR2 and STX5 - Danio rerio [Reaction:R-SSC-5694413] SEC4C,D bind GOSR2 and STX5 - Sus scrofa [Reaction:R-CFA-5694413] SEC4C,D bind GOSR2 and STX5 - Canis familiaris [Reaction:R-RNO-5694413] SEC4C,D bind GOSR2 and STX5 - Rattus norvegicus [Reaction:R-MMU-5694413] SEC4C,D bind GOSR2 and STX5 - Mus musculus
output	[Complex:R-HSA-5694245] SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane]
releaseDate	2015-09-22
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6791049] Gillespie, Marc E, 2015-08-17
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-5694413
summation	[Summation:5694387] SEC24 isoforms C and D are required in conjunction with SEC2...

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(hasEvent)

[Pathway:R-HSA-5694530] Cargo concentration in the ER