SEC4C,D bind GOSR2 and STX5

Stable Identifier
R-HSA-5694413
Type
Reaction [binding]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
ReviewStatus
5/5
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SEC4C,D bind GOSR2 and STX5
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SEC24 isoforms C and D are required in conjunction with SEC23A for packaging the t-SNARES STX5 and GOSR2 into COPII vesicles for transport to the Golgi (Mancias and Goldberg, 2008).
Literature References
PubMed ID Title Journal Year
18843296 Structural basis of cargo membrane protein discrimination by the human COPII coat machinery

Goldberg, J, Mancias, JD

EMBO J. 2008
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Orthologous Events
SEC4C,D bind GOSR2 and STX5 (Bos taurus)
SEC4C,D bind GOSR2 and STX5 (Caenorhabditis elegans)
SEC4C,D bind GOSR2 and STX5 (Canis familiaris)
SEC4C,D bind GOSR2 and STX5 (Dictyostelium discoideum)
SEC4C,D bind GOSR2 and STX5 (Drosophila melanogaster)
SEC4C,D bind GOSR2 and STX5 (Gallus gallus)
SEC4C,D bind GOSR2 and STX5 (Mus musculus)
SEC4C,D bind GOSR2 and STX5 (Plasmodium falciparum)
SEC4C,D bind GOSR2 and STX5 (Rattus norvegicus)
SEC4C,D bind GOSR2 and STX5 (Saccharomyces cerevisiae)
SEC4C,D bind GOSR2 and STX5 (Schizosaccharomyces pombe)
SEC4C,D bind GOSR2 and STX5 (Sus scrofa)
SEC4C,D bind GOSR2 and STX5 (Xenopus tropicalis)
Authored
Rothfels, K  (2015-04-18)
Reviewed
Gillespie, ME  (2015-08-18)
Created
Rothfels, K  (2015-05-21)
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